NR1H3 Produkte
(Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
Kategorien
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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Ausgewählte NR1H3 Kategorien
NR1H3 Antikörper
High quality antibodies with extensive validation data.
NR1H3 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR1H3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NR1H3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN7217836
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN523441
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Chicken, Cow, Dog, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Applikation
WB, IHC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN462212
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene NR1H3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958254
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969010
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958253
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NR1H3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312934
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2727545
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7395752
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NR1H3 Produkten
: "Novel Lactobacillus reuteri HI120 Affects Lipid Metabolism in C57BL/6 Obese Mice." in: Frontiers in veterinary science, Vol. 7, pp. 560241, (2020) (PubMed).: "LXR/RXR pathway signaling associated with triple-negative breast cancer in African American women." in: Breast cancer (Dove Medical Press), Vol. 11, pp. 1-12, (2019) (PubMed).
: "PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells." in: Hepatology communications, Vol. 3, Issue 9, pp. 1191-1204, (2019) (PubMed).
: "Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease." in: The Korean journal of internal medicine, (2018) (PubMed).
: "G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).
: "Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 29, pp. 8182-7, (2016) (PubMed).
: "AMPK activates LXRα and ABCA1 expression in human macrophages." in: The international journal of biochemistry & cell biology, Vol. 78, pp. 1-9, (2016) (PubMed).
: "Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 35, Issue 4, pp. 1133-44, (2015) (PubMed).
: "Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 503-8, (2014) (PubMed).
: "Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease." in: Digestive diseases and sciences, Vol. 59, Issue 12, pp. 2975-82, (2014) (PubMed).
Synonyme und alternative Namen zu NR1H3
nuclear receptor subfamily 1 group H member 3 (NR1H3), nuclear receptor subfamily 1 group H member 3 (nr1h3), nuclear receptor subfamily 1, group H, member 3 (Nr1h3), nuclear receptor subfamily 1, group H, member 3 (nr1h3), AU018371, im:7141239, LXR, LXR-a, LXR-alpha, LXRA, LXRalpha, NR1H3, RLD-1, RLD1, Unr1, wu:fd59b01, zgc:113339, zgc:158542Bezeichner auf Proteinebene für NR1H3
- nuclear receptor subfamily 1, group H, member 3
- oxysterols receptor LXR-alpha-like
- liver X nuclear receptor alpha variant 1
- oxysterols receptor LXR-alpha
- LXR alpha
- liver X receptor alpha
- ubiquitously-expressed nuclear receptor 1
- nuclear orphan receptor LXR-alpha
- nuclear receptor subfamily 1 group H member 3
- LXRalpha
- liver X receptor
- lxr
- nuclear oxysterol receptor LxR-alpha
- RLD-1
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