NR1I3 Produkte
(Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
Kategorien
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte NR1I3 Kategorien
NR1I3 Antikörper
High quality antibodies with extensive validation data.
NR1I3 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR1I3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NR1I3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC
Validierungen
- (5)
Kat. Nr.
ABIN7259546
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7161898
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN462245
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene NR1I3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969015
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969014
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969016
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NR1I3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312943
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312942
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7418869
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NR1I3 Produkten
: "Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine." in: British journal of pharmacology, Vol. 172, Issue 5, pp. 1263-76, (2015) (PubMed).Synonyme und alternative Namen zu NR1I3
nuclear receptor subfamily 1 group I member 3 (NR1I3), nuclear receptor subfamily 1, group I, member 3 (Nr1i3), AA209988, AI551208, CAR, CAR-beta, CAR1, Care2, CXR, ESTM32, MB67Bezeichner auf Proteinebene für NR1I3
- constitutive androstane receptor
- constitutively transactivates RAREs
- nuclear receptor subfamily 1 group I member 3
- orphan nuclear receptor MB67
- constitutive androstane receptor NR1I3
- nuclear receptor constitutive active receptor
- strain Fischer nuclear receptor (CAR)
- constitutive activator of retinoid response
- constitutive active receptor
- constitutive active response
- constitutive androstane nuclear receptor variant 2
- constitutive androstane nuclear receptor variant 3
- constitutive androstane nuclear receptor variant 4
- constitutive androstane nuclear receptor variant 5
- orphan nuclear hormone receptor
- xenobiotic receptor
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