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NSMCE2 Produkte

(E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Kategorien

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).

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Ausgewählte NSMCE2 Kategorien

NSMCE2 Antikörper

High quality antibodies with extensive validation data.

NSMCE2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NSMCE2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN531598
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (1)
Kat. Nr. ABIN7150959
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (1)
Kat. Nr. ABIN3185961
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NSMCE2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313078
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3094191
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3136789
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NSMCE2 Produkten

Verver, Zheng, Speijer, Hoebe, Dekker, Repping, Stap, Hamer: "Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).

Yusof, Mehde, Mehdi, Raus, Ghazali, Rahman: "Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals." in: Biomedical and environmental sciences : BES, Vol. 28, Issue 9, pp. 660-5, (2015) (PubMed).

Ji, Bian, Yu, Yuan, Liu, Yu, Li, Zhu, Jia, Guan, Zhang, Meng, Jin, Bai, Yu, Lee, Sun, Fu: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).

Chung, Leonhardt, Rippe: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).

Synonyme und alternative Namen zu NSMCE2

NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L), Smc5-6 complex non-SMC subunit 2 (nse2), 1110014D18Rik, AI661537, C8orf36, MMS21, Non-SMC element 2, NSE2, RGD1305156, ZMIZ7

Bezeichner auf Proteinebene für NSMCE2

  • E3 SUMO-protein ligase NSE2
  • MMS21 homolog
  • non-structural maintenance of chromosomes element 2 homolog
  • non-SMC element 2 homolog
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • zinc finger, MIZ-type containing 7
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2
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