NSMCE2 Produkte
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
Kategorien
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
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Ausgewählte NSMCE2 Kategorien
NSMCE2 Antikörper
High quality antibodies with extensive validation data.
NSMCE2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NSMCE2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN531598
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN7150959
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN3185961
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NSMCE2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313078
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094191
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136789
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NSMCE2 Produkten
: "Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).: "Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals." in: Biomedical and environmental sciences : BES, Vol. 28, Issue 9, pp. 660-5, (2015) (PubMed).
: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).
: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).
Synonyme und alternative Namen zu NSMCE2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2), NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L), Smc5-6 complex non-SMC subunit 2 (nse2), 1110014D18Rik, AI661537, C8orf36, MMS21, Non-SMC element 2, NSE2, RGD1305156, ZMIZ7Bezeichner auf Proteinebene für NSMCE2
- E3 SUMO-protein ligase NSE2
- MMS21 homolog
- non-structural maintenance of chromosomes element 2 homolog
- non-SMC element 2 homolog
- hMMS21
- methyl methanesulfonate sensitivity gene 21
- zinc finger, MIZ-type containing 7
- non-SMC element 2 homolog (MMS21, S. cerevisiae)
- Non-structural maintenance of chromosomes element 2
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