NUAK1 Produkte
(NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
Kategorien
Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in 392' and is recruited to the CDKN1A/WAF1 promoter to participate to transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
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Ausgewählte NUAK1 Kategorien
NUAK1 Antikörper
High quality antibodies with extensive validation data.
NUAK1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NUAK1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Hamster, Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN392639
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN392640
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN716396
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NUAK1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6227500
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NUAK1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313130
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313129
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509049
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NUAK1 Produkten
: "Regulation of ploidy and senescence by the AMPK-related kinase NUAK1." in: The EMBO journal, Vol. 29, Issue 2, pp. 376-86, (2010) (PubMed).: "The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis." in: Experimental physiology, Vol. 92, Issue 1, pp. 207-17, (2007) (PubMed).
: "ARK5 is a tumor invasion-associated factor downstream of Akt signaling." in: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3526-35, (2004) (PubMed).
: "Strong association of ARK5 with tumor invasion and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 23, Issue 2, pp. 263-8, (2004) (PubMed).
: "ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation." in: Oncogene, Vol. 22, Issue 40, pp. 6177-82, (2003) (PubMed).
: "Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 48-53, (2002) (PubMed).
Synonyme und alternative Namen zu NUAK1
NUAK family kinase 1 (NUAK1), NUAK family, SNF1-like kinase, 1 (Nuak1), ARK5, AU014801, AW494241, B230104P22Rik, Omphk1Bezeichner auf Proteinebene für NUAK1
- AMP-activated protein kinase family member 5
- AMPK-related protein kinase 5
- NUAK family SNF1-like kinase 1
- omphalocele kinase 1
- ZNUAK family, SNF1-like kinase, 1
Haben Sie etwas anderes gesucht?
- NTX-I
- NTSR2
- NTSR1
- NTRK3
- Nth Endonuclease III-Like 1
- NTAN1
- NTA1
- NT5M
- NT5DC4
- NT5DC3
- NT5C3L
- NT5C3
- NT5C1B
- NT5C1A
- NT5C
- NT-ProBNP
- NSUN7
- NSUN6
- NSUN5P2
- NSUN5P1
- NUAK2
- NUB1
- Nubbin
- NUBP2
- NUBPL
- NUCB2
- NUCB2
- Nucleaoside Diphosphate Kinase
- Nuclear Antigen
- Nuclear Casein Kinase and Cyclin-Dependent Kinase Substrate 1
- Nuclear Factor 1
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha
- Nuclear LaMiN Family Member (Lmn-1)
- Nuclear Marker
- Nuclear Matrix Protein 22
- Nuclear Receptor Subfamily 1, Group D, Member 2
- Nuclear Receptor Subfamily 1, Group H, Member 2/3
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Transcription Factor Y, beta
- Nuclease
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