NUB1 Produkte
(Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
Kategorien
This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
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Ausgewählte NUB1 Kategorien
NUB1 Antikörper
High quality antibodies with extensive validation data.
NUB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NUB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Dog, Human, Monkey, Rat
Applikation
WB, IHC, IHC (p), IF, FACS
Validierungen
- (7)
Kat. Nr.
ABIN1490743
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN389078
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6263785
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NUB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381369
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Validierungen
Kat. Nr.
ABIN1144444
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NUB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313139
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313137
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3084737
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NUB1 Produkten
: "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32905-13, (2003) (PubMed).: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." in: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).
: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).
Synonyme und alternative Namen zu NUB1
negative regulator of ubiquitin-like proteins 1 (Nub1), negative regulator of ubiquitin like proteins 1 (NUB1), 4931404D21Rik, 6330412F12Rik, BS4, NUB1L, NY-REN-18, NYREN18Bezeichner auf Proteinebene für NUB1
- NEDD8 ultimate buster 1
- NEDD8 ultimate buster-1
- NY-REN-18 antigen
- renal carcinoma antigen NY-REN-18
- Nedd8 ultimate buster-1
Haben Sie etwas anderes gesucht?
- NUAK2
- NUAK1
- NTX-I
- NTSR2
- NTSR1
- NTRK3
- Nth Endonuclease III-Like 1
- NTAN1
- NTA1
- NT5M
- NT5DC4
- NT5DC3
- NT5C3L
- NT5C3
- NT5C1B
- NT5C1A
- NT5C
- NT-ProBNP
- NSUN7
- NSUN6
- Nubbin
- NUBP2
- NUBPL
- NUCB2
- NUCB2
- Nucleaoside Diphosphate Kinase
- Nuclear Antigen
- Nuclear Casein Kinase and Cyclin-Dependent Kinase Substrate 1
- Nuclear Factor 1
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha
- Nuclear LaMiN Family Member (Lmn-1)
- Nuclear Marker
- Nuclear Matrix Protein 22
- Nuclear Receptor Subfamily 1, Group D, Member 2
- Nuclear Receptor Subfamily 1, Group H, Member 2/3
- Nuclear Receptor Subfamily 2, Group C, Member 1
- Nuclear Transcription Factor Y, beta
- Nuclease
- Nuclease P1
- Nuclease S1
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