NUMB Produkte
(Numb Homolog (NUMB))
Kategorien
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte NUMB Kategorien
NUMB Antikörper
High quality antibodies with extensive validation data.
NUMB ELISA Kits
Reliable ELISA kits for a wide range of species.
NUMB Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NUMB Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN6144943
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC, IF, FACS
Validierungen
- (9)
Kat. Nr.
ABIN184679
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN563731
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene NUMB ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4884024
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6385253
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NUMB Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313212
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405789
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405792
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NUMB Produkten
: "Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer." in: Cell, Vol. 178, Issue 1, pp. 135-151.e19, (2019) (PubMed).: "Effect of experimentally induced hypothyroidism during gestation period on activity dependent neurotrophic factor (ADNF) in newborn rat brain tissue." in: Hormone molecular biology and clinical investigation, Vol. 36, Issue 3, (2018) (PubMed).
: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." in: Molecular neurobiology, (2016) (PubMed).
: "Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway." in: Stem cell reports, Vol. 5, Issue 5, pp. 866-80, (2015) (PubMed).
: "Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy." in: Journal of physiology and biochemistry, Vol. 71, Issue 2, pp. 217-26, (2015) (PubMed).
: "The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1." in: Nature medicine, Vol. 20, Issue 1, pp. 80-6, (2014) (PubMed).
: "NUMB controls p53 tumour suppressor activity." in: Nature, Vol. 451, Issue 7174, pp. 76-80, (2008) (PubMed).
: "Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas." in: International journal of immunopathology and pharmacology, Vol. 20, Issue 4, pp. 779-89, (2008) (PubMed).
: "Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3." in: Developmental cell, Vol. 13, Issue 1, pp. 15-28, (2007) (PubMed).
: "Asymmetric localization of numb in the chick somite and the influence of myogenic signals." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 235, Issue 3, pp. 633-45, (2006) (PubMed).
Synonyme und alternative Namen zu NUMB
NUMB, endocytic adaptor protein (NUMB), numb homolog (Drosophila) (Numb), NUMB, endocytic adaptor protein (Numb), numb homolog (Drosophila) (numb), C14orf41, c14_5527, Nb, S171Bezeichner auf Proteinebene für NUMB
- h-Numb
- protein numb homolog
- numb gene homolog
- numb homolog
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