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NUMB Produkte

(Numb Homolog (NUMB))

Kategorien

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte NUMB Kategorien

NUMB Antikörper

High quality antibodies with extensive validation data.

NUMB ELISA Kits

Reliable ELISA kits for a wide range of species.

NUMB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NUMB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN6144943
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation ELISA, IHC, IF, FACS
Validierungen
  • (9)
Kat. Nr. ABIN184679
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN563731
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NUMB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884024
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6385253
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NUMB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313212
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7405789
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7405792
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NUMB Produkten

Wang, Xiang, Liu, He, Randle, Zhang, Dongre, Sachs, Clark, Tao, Chen, Botchkarev, Xie, Dai, Clevers, Li, Livingston: "Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer." in: Cell, Vol. 178, Issue 1, pp. 135-151.e19, (2019) (PubMed).

Cesur, Eren, Eren, Ergin, Ek, Yıldız, Şirinyıldız, Gök Balcı, Ongel: "Effect of experimentally induced hypothyroidism during gestation period on activity dependent neurotrophic factor (ADNF) in newborn rat brain tissue." in: Hormone molecular biology and clinical investigation, Vol. 36, Issue 3, (2018) (PubMed).

Lenihan, Saha, Heimer-McGinn, Cryan, Feng, Young: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." in: Molecular neurobiology, (2016) (PubMed).

Mah, Soloff, Hedrick, Mariani: "Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway." in: Stem cell reports, Vol. 5, Issue 5, pp. 866-80, (2015) (PubMed).

Wu, Zhang, Liu, Yan, Liu, Xie, Zhang, Sun, Ke, Zhou: "Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy." in: Journal of physiology and biochemistry, Vol. 71, Issue 2, pp. 217-26, (2015) (PubMed).

Li, Fu, Zhang, Zhang, Xu, Ma, Li, Song: "The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1." in: Nature medicine, Vol. 20, Issue 1, pp. 80-6, (2014) (PubMed).

Colaluca, Tosoni, Nuciforo, Senic-Matuglia, Galimberti, Viale, Pece, Di Fiore: "NUMB controls p53 tumour suppressor activity." in: Nature, Vol. 451, Issue 7174, pp. 76-80, (2008) (PubMed).

Maiorano, Favia, Pece, Resta, Maisonneuve, Di Fiore, Capodiferro, Urbani, Viale: "Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas." in: International journal of immunopathology and pharmacology, Vol. 20, Issue 4, pp. 779-89, (2008) (PubMed).

Nishimura, Kaibuchi: "Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3." in: Developmental cell, Vol. 13, Issue 1, pp. 15-28, (2007) (PubMed).

Holowacz, Zeng, Lassar: "Asymmetric localization of numb in the chick somite and the influence of myogenic signals." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 235, Issue 3, pp. 633-45, (2006) (PubMed).

Synonyme und alternative Namen zu NUMB

NUMB, endocytic adaptor protein (NUMB), numb homolog (Drosophila) (Numb), NUMB, endocytic adaptor protein (Numb), numb homolog (Drosophila) (numb), C14orf41, c14_5527, Nb, S171

Bezeichner auf Proteinebene für NUMB

  • h-Numb
  • protein numb homolog
  • numb gene homolog
  • numb homolog
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