OAS1B Produkte
(2'-5' Oligoadenylate Synthetase 1B (OAS1B))
Kategorien
This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].
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Ausgewählte OAS1B Kategorien
OAS1B Antikörper
High quality antibodies with extensive validation data.
Empfohlene OAS1B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
West Nile Virus (WNV)
Applikation
IF, ELISA, WB
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN2477148
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene OAS1B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3122767
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren OAS1B Produkten
: "Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein." in: The Journal of general virology, Vol. 86, Issue Pt 2, pp. 405-12, (2005) (PubMed).: "West Nile virus: a growing concern?" in: The Journal of clinical investigation, Vol. 113, Issue 8, pp. 1102-7, (2004) (PubMed).
: "Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54533-41, (2004) (PubMed).
Synonyme und alternative Namen zu OAS1B
2'-5' oligoadenylate synthetase 1B (Oas1b), 2-5 oligoadenylate synthetase 1B (Oas1b), (2-5')oligo(A) synthase 1B, 2-5A synthase 1B, Flv, L1, Mmu-L1, Oas1, Oias-2, Oias2, WnvBezeichner auf Proteinebene für OAS1B
- (2-5')oligo(A) synthase 1B
- (2-5')oligo(A) synthetase 1b
- 2',5'-oligoadenylate synthetase-like 1
- 2'-5'-oligoadenylate synthase 1B
- 2'-5'-oligoadenylate synthase-like protein 1
- 2'-5'-oligoadenylate synthetase-like protein 1
- 2-5A synthase 1B
- 2-5A synthetase 1B
- Flavivirus resistance
- inactive 2'-5'-oligoadenylate synthase 1B
- 2'5' oligoadenylate synthetase-2
- 25 oligoadenylate synthetase-2
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