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OPCML Produkte

(Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Kategorien

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte OPCML Kategorien

OPCML Antikörper

High quality antibodies with extensive validation data.

OPCML Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene OPCML Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1881594
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), IHC
Validierungen
  • (2)
Kat. Nr. ABIN1804627
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN6263790
Menge 100 μL
Datenblatt Datenblatt

Empfohlene OPCML ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884030
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6386192
Menge 96 tests
Datenblatt Datenblatt

Empfohlene OPCML Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313406
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320058
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7317147
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren OPCML Produkten

Birtley, Alomary, Zanini, Antony, Maben, Weaver, Von Arx, Mura, Marinho, Lu, Morecroft, Karali, Chayen, Tate, Jurewicz, Stern, Recchi, Gabra: "Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions." in: Nature communications, Vol. 10, Issue 1, pp. 3134, (2019) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Wang, Zhu, Song, Chen, Chen: "Comparison of gene expression profiles between primary tumor and metastatic lesions in gastric cancer patients using laser microdissection and cDNA microarray." in: World journal of gastroenterology, Vol. 12, Issue 43, pp. 6949-54, (2006) (PubMed).

Sellar, Watt, Rabiasz, Stronach, Li, Miller, Massie, Miller, Contreras-Moreira, Scott, Brown, Williams, Bates, Smyth, Gabra: "OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer." in: Nature genetics, Vol. 34, Issue 3, pp. 337-43, (2003) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Synonyme und alternative Namen zu OPCML

opioid binding protein/cell adhesion molecule like (OPCML), opioid binding protein/cell adhesion molecule-like (Opcml), 2900075O15Rik, 3732419F12, AI844366, B930023M13Rik, C230027C17, Gm181, IGLON1, OBCAM, Obcam, OPCM

Bezeichner auf Proteinebene für OPCML

  • IgLON family member 1
  • opioid binding protein/cell adhesion molecule-like preprotein
  • opioid-binding protein/cell adhesion molecule
  • opioid binding cell adhesion molecule
  • OBCAM
  • opioid-binding cell adhesion molecule
  • opioid-binding protein/cell adhesion molecule-like
  • OBCAM alpha 1 isoform
  • OBCAM protein gamma isoform
  • neurite inhibitor GP55-A
  • opioid-binding protein/cell adhesion molecule homolog
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