ORAI1 Produkte
(ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
Kategorien
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011].
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Ausgewählte ORAI1 Kategorien
ORAI1 Antikörper
High quality antibodies with extensive validation data.
ORAI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene ORAI1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, IHC, FACS, IF, LCI, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7043408
Menge
25 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7146306
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6263901
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ORAI1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1124739
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1124740
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1124741
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ORAI1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3117264
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3125369
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ORAI1 Produkten
: "Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion." in: Frontiers in physiology, Vol. 9, pp. 813, (2018) (PubMed).: "Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells." in: The Journal of biological chemistry, Vol. 291, Issue 40, pp. 21148-21159, (2016) (PubMed).
: "Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression." in: Cell reports, Vol. 12, Issue 2, pp. 203-16, (2015) (PubMed).
: "Molecular mechanisms of spontaneous and directed mast cell motility." in: Journal of leukocyte biology, Vol. 92, Issue 5, pp. 1029-41, (2012) (PubMed).
: "Selective activation of the transcription factor NFAT1 by calcium microdomains near Ca2+ release-activated Ca2+ (CRAC) channels." in: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 14795-803, (2011) (PubMed).
: "POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19234-9, (2011) (PubMed).
: "Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome." in: Human molecular genetics, Vol. 19, Issue 20, pp. 4026-42, (2010) (PubMed).
: "Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8." in: Molecular pharmacology, Vol. 75, Issue 4, pp. 830-42, (2009) (PubMed).
: "Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis." in: Nature cell biology, Vol. 11, Issue 12, pp. 1465-72, (2009) (PubMed).
: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).
Synonyme und alternative Namen zu ORAI1
ORAI calcium release-activated calcium modulator 1 (ORAI1), ORAI calcium release-activated calcium modulator 1 (Orai1), ORAI calcium release-activated calcium modulator 1b (orai1b), ORAI calcium release-activated calcium modulator 1 S homeolog (orai1.S), ORAI calcium release-activated calcium modulator 1 (orai1), CRACM1, D730049H07Rik, im:7146264, LOC100218031, orai-1, orai1, ORAI1, orai2, ORAT1, RGD1311873, TMEM142A, Tmem142a, tmem142a, zgc:109721Bezeichner auf Proteinebene für ORAI1
- calcium release-activated calcium channel protein 1
- calcium release-activated calcium modulator 1
- protein orai-1
- transmembrane protein 142A
- calcium release-activated calcium channel 1
- ORAI calcium release-activated calcium modulator 1
- protein orai-2
- transmembrane protein 142B
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