ORC1 Produkte
(Origin Recognition Complex, Subunit 1 (ORC1L))
Kategorien
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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Ausgewählte ORC1 Kategorien
ORC1 Antikörper
High quality antibodies with extensive validation data.
ORC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ORC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7252684
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN518535
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN108601
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene ORC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313648
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094294
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3137604
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ORC1 Produkten
: "SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6306-16, (2013) (PubMed).: "The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication." in: Journal of cell science, Vol. 123, Issue Pt 16, pp. 2743-9, (2010) (PubMed).
: "Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 15397-408, (2001) (PubMed).
: "Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus." in: The EMBO journal, Vol. 20, Issue 16, pp. 4588-602, (2001) (PubMed).
Synonyme und alternative Namen zu ORC1
Origin recognition complex subunit 1 (Orc1), origin recognition complex subunit 1 (Orc1), origin recognition complex subunit 1 (ORC1), origin recognition complex subunit 1 L homeolog (orc1.L), origin recognition complex, subunit 1 (Orc1), AA545195, CG10667, Dmel\\CG10667, DmORC1, DmOrc1, DmOrc1p, dORC1, HSORC1, MmORC1, ORC, ORC1, orc1, ORC1L, orc1l, Orc1l, PARC1, rDmORC, xorc1Bezeichner auf Proteinebene für ORC1
- CG10667-PA
- Orc1-PA
- origin recognition complex 1
- origin recognition complex subunit 1
- origin recognition complex, subunit 1 homolog
- replication control protein 1
- origin recognition complex protein 1
- origin recognition complex, subunit 1-like
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