Orthodenticle Homeobox 2 Produkte
(Orthodenticle Homeobox 2 (OTX2))
Kategorien
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012].
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Ausgewählte Orthodenticle Homeobox 2 Kategorien
Orthodenticle Homeobox 2 Antikörper
High quality antibodies with extensive validation data.
Orthodenticle Homeobox 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Orthodenticle Homeobox 2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Orthodenticle Homeobox 2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN969332
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7074952
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Orthodenticle Homeobox 2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969088
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1137430
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1137429
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Orthodenticle Homeobox 2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124276
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3085429
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3121044
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Orthodenticle Homeobox 2 Produkten
: "Stem cells from human exfoliated deciduous tooth exhibit stromal-derived inducing activity and lead to generation of neural crest cells from human embryonic stem cells." in: Cell journal, Vol. 17, Issue 1, pp. 37-48, (2015) (PubMed).: "Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138416, (2015) (PubMed).
: "Endogenous regeneration of damaged retinal pigment epithelium following low dose sodium iodate administration: an insight into the role of glial cells in retinal repair." in: Experimental eye research, Vol. 112, pp. 68-78, (2013) (PubMed).
: "OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas." in: Cancer research, Vol. 70, Issue 1, pp. 181-91, (2010) (PubMed).
: "SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 26933-44, (2010) (PubMed).
: "The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons." in: Brain : a journal of neurology, Vol. 133, Issue Pt 7, pp. 2022-31, (2010) (PubMed).
: "A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency." in: Human genetics, Vol. 127, Issue 6, pp. 721-9, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases." in: The British journal of ophthalmology, Vol. 94, Issue 8, pp. 1100-4, (2010) (PubMed).
: "Differential CRX and OTX2 expression in human retina and retinoblastoma." in: Journal of neurochemistry, Vol. 111, Issue 1, pp. 250-63, (2009) (PubMed).
Synonyme und alternative Namen zu Orthodenticle Homeobox 2
orthodenticle homeobox 2 (OTX2), orthodenticle homeobox 2 (Otx2), orthodenticle homeobox 2 (otx2), orthodenticle homeobox 2 S homeolog (otx2.S), orthodenticle homeobox 2 L homeolog (otx2.L), CPHD6, E130306E05Rik, id:ibd2915, MCOPS5, otx-2, otx2, Xotx-2, Xotx2, zgc:136535, zotx-2, zOtx2Bezeichner auf Proteinebene für Orthodenticle Homeobox 2
- homeobox protein OTX2
- orthodenticle homolog 2
- homeobox Otx2
- etID309955.17
- homeobox protein OTX2-A
- orthodenticle 2-A
- orthodenticle-A-like protein A
- xOTX2-A
- orthodenticle homeobox protein 2
- homeobox protein OTX2-B
- orthodenticle 2-B
- orthodenticle-A-like protein B
- xOTX2-B
- LOW QUALITY PROTEIN: homeobox protein OTX2
- orthodenticle 2
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