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Osteoactivin Produkte

(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Osteoactivin Kategorien

Osteoactivin Antikörper

High quality antibodies with extensive validation data.

Osteoactivin ELISA Kits

Reliable ELISA kits for a wide range of species.

Osteoactivin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Osteoactivin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validierungen
  • (6)
  • (2)
  • (1)
Kat. Nr. ABIN749093
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN1724859
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN523856
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Osteoactivin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969089
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN2748458
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5564592
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Osteoactivin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274753
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274754
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7491429
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Osteoactivin Produkten

Neal, Boyle, Budge, Safadi, Richardson: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).

Arosarena, Barr, Thorpe, Yankey, Tarr, Safadi: "Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases." in: Journal of cellular physiology, Vol. 233, Issue 1, pp. 409-421, (2017) (PubMed).

Oyewumi, Manickavasagam, Novak, Wehrung, Paulic, Moussa, Sondag, Safadi: "Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells." in: Oncotarget, Vol. 7, Issue 12, pp. 13932-44, (2017) (PubMed).

Arosarena, Dela Cadena, Denny, Bryant, Barr, Thorpe, Safadi: "Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas." in: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1761-70, (2016) (PubMed).

Frara, Abdelmagid, Tytell, Amin, Popoff, Safadi, Barbe: "Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping." in: BMC musculoskeletal disorders, Vol. 17, pp. 34, (2016) (PubMed).

Lin, Li, Xing, Hu, Liang, Han, Wang, Hawke, Wang, Zhang, Wei, Ma, Park, Zhou, Zhou, Hu, Zhou, Marks, Liang, Hung, Lin, Yang: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." in: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).

Kramer, Wegdam, Donker-Koopman, Ottenhoff, Gaspar, Verhoek, Nelson, Gabriel, Kallemeijn, Boot, Laman, Vissers, Cox, Pavlova, Moran, Aerts, van Eijk: "Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models." in: FEBS open bio, Vol. 6, Issue 9, pp. 902-13, (2016) (PubMed).

Ruan, Li, Nie, Zhou, Zou: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).

Abdelmagid, Sondag, Moussa, Belcher, Yu, Stinnett, Novak, Mbimba, Khol, Hankenson, Malcuit, Safadi: "Mutation in Osteoactivin Promotes Receptor Activator of NF?B Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function." in: The Journal of biological chemistry, Vol. 290, Issue 33, pp. 20128-46, (2015) (PubMed).

Torres, Linares, Alejandre, Palomino-Morales, Martin, Delgado, Martinez, Perales: "The potential role of the glycoprotein osteoactivin/glycoprotein nonmetastatic melanoma protein B in pancreatic cancer." in: Pancreas, Vol. 44, Issue 2, pp. 302-10, (2015) (PubMed).

Synonyme und alternative Namen zu Osteoactivin

glycoprotein nmb (Gpnmb), glycoprotein nmb (GPNMB), glycoprotein (transmembrane) nmb (Gpnmb), glycoprotein nmb L homeolog (gpnmb.L), DC-HIL, Dchil, HGFIN, ipd, NMB

Bezeichner auf Proteinebene für Osteoactivin

  • osteoactivin
  • transmembrane glycoprotein NMB
  • glycoprotein NMB
  • glycoprotein nmb-like protein
  • transmembrane glycoprotein HGFIN
  • dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand
  • dendritic cell-associated transmembrane protein
  • iris pigment dispersion
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