PABPC4 Produkte
(Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
Kategorien
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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Ausgewählte PABPC4 Kategorien
PABPC4 Antikörper
High quality antibodies with extensive validation data.
Empfohlene PABPC4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN6145149
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IP
Validierungen
- (2)
Kat. Nr.
ABIN6264006
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Bat, Dog, Horse, Human, Monkey, Mouse, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN202848
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PABPC4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6229821
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PABPC4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3085250
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PABPC4 Produkten
: "N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis." in: Nature communications, Vol. 10, Issue 1, pp. 4596, (2019) (PubMed).: "Identification and Characterization of Potential Biomarkers by Quantitative Tissue Proteomics of Primary Lung Adenocarcinoma." in: Molecular & cellular proteomics : MCP, Vol. 15, Issue 7, pp. 2396-410, (2016) (PubMed).
: "Cytoplasmic poly(A) binding protein C4 serves a critical role in erythroid differentiation." in: Molecular and cellular biology, Vol. 34, Issue 7, pp. 1300-9, (2014) (PubMed).
: "Enhanced translation of mRNAs encoding proteins involved in mRNA translation during recovery from heat shock." in: PLoS ONE, Vol. 8, Issue 5, pp. e64171, (2013) (PubMed).
: "Depletion of nuclear poly(A) binding protein PABPN1 produces a compensatory response by cytoplasmic PABP4 and PABP5 in cultured human cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e53036, (2013) (PubMed).
: "Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 39, Issue 8, pp. 369-74, (2012) (PubMed).
: "N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD." in: Nucleic acids research, Vol. 40, Issue 3, pp. 1251-66, (2012) (PubMed).
: "Cytoplasmic poly(A) binding proteins regulate telomerase activity and cell growth in human papillomavirus type 16 E6-expressing keratinocytes." in: Journal of virology, Vol. 84, Issue 24, pp. 12934-44, (2010) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
Synonyme und alternative Namen zu PABPC4
polyadenylate-binding protein 4 (Bm1_06880), poly(A) binding protein, cytoplasmic 4 (Pabpc4), poly(A) binding protein, cytoplasmic 4 (inducible form) (pabpc4), poly(A) binding protein cytoplasmic 4 L homeolog (pabpc4.L), poly(A) binding protein cytoplasmic 4 (PABPC4), APP-1, APP1, cb12, ePAB, ePABP, iPABP, PABP, PABP4, sb:cb12Bezeichner auf Proteinebene für PABPC4
- polyadenylate-binding protein 4
- poly(A) binding protein, cytoplasmic 4 (inducible form)
- PABP-4
- activated-platelet protein 1
- inducible poly(A)-binding protein
- poly(A)-binding protein 4
- poly A binding protein, cytoplasmic 4
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