PAICS Produkte
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Kategorien
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte PAICS Kategorien
PAICS Antikörper
High quality antibodies with extensive validation data.
PAICS Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PAICS Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN656869
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7160326
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7237569
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene PAICS ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6229169
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PAICS Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124444
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313911
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2131021
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PAICS Produkten
: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." in: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).: "Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders." in: Molecular genetics and metabolism, Vol. 108, Issue 3, pp. 178-89, (2013) (PubMed).
: "Transiently transfected purine biosynthetic enzymes form stress bodies." in: PLoS ONE, Vol. 8, Issue 2, pp. e56203, (2013) (PubMed).
Synonyme und alternative Namen zu PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (PAICS), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (paics), multifunctional protein ADE2 (LOC551966), multifunctional protein ADE2 (Tsp_02239a), multifunctional protein ADE2 (Tsp_02239), phosphoribosylaminoimidazole carboxylase (CNE02500), phosphoribosylaminoimidazole carboxylase (purC/E), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase (Paics), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog (paics.2.L), phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), 2610511I09Rik, ADE2, ade2, ADE2H1, Ade2h1, AIRC, Airc, airc, AS, cb293, DDBDRAFT_0218550, DDBDRAFT_0230088, DDB_0218550, DDB_0230088, GB14262, paics, PAIS, pais, sb:cb293, wu:fa28a05Bezeichner auf Proteinebene für PAICS
- multifunctional protein ADE2
- phosphoribosylaminoimidazole carboxylase
- phosphoribosylaminoimidazolesuccinocarboxamide synthase
- AIR carboxylase domain
- AIR carboxylase
- SAICAR synthetase
- multifunctional protein ADE2H1
- phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase
- Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase
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