PARL Produkte
(Presenilin Associated, Rhomboid-Like (PARL))
Kategorien
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte PARL Kategorien
PARL Antikörper
High quality antibodies with extensive validation data.
PARL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PARL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN2782038
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN634971
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7164273
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PARL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314017
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314016
Menge
25 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PARL Produkten
: "The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 11, pp. 1658-65, (2013) (PubMed).: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).
: "Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling." in: Cell, Vol. 126, Issue 1, pp. 163-75, (2006) (PubMed).
: "Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18562-7, (2006) (PubMed).
: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).
: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).
Synonyme und alternative Namen zu PARL
presenilin associated rhomboid like (PARL), presenilin associated, rhomboid-like (Parl), presenilin associated rhomboid like (Parl), presenilin associated, rhomboid-like a (parla), D16Ertd607e, parl, PRO2207, PSARL, Psarl, PSARL1, PSENIP2, RHBDS1, zgc:112986Bezeichner auf Proteinebene für PARL
- mitochondrial intramembrane cleaving protease PARL
- mitochondrial intramembrane-cleaving protease PARL
- presenilins-associated rhomboid-like protein, mitochondrial
- rhomboid 7 homolog 1
- presenilin associated, rhomboid-like isoform 1 preproprotein
- presenilin associated, rhomboid-like preproprotein
- parlb
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