p107 Produkte
(Retinoblastoma-Like 1 (p107) (RBL1))
Kategorien
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte p107 Kategorien
p107 Antikörper
High quality antibodies with extensive validation data.
p107 ELISA Kits
Reliable ELISA kits for a wide range of species.
p107 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene p107 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN389640
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, PLA
Validierungen
- (3)
Kat. Nr.
ABIN562602
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1881732
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene p107 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969920
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1155324
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene p107 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317569
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094884
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3135610
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren p107 Produkten
: "XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies." in: Oncotarget, Vol. 9, Issue 77, pp. 34567-34581, (2018) (PubMed).: "p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation." in: Bone, Vol. 69, pp. 47-54, (2014) (PubMed).
: "The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1205-18, (2013) (PubMed).
: "B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29863-73, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).
: "p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2." in: The Journal of cell biology, Vol. 168, Issue 1, pp. 55-66, (2005) (PubMed).
: "The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain." in: The Journal of biological chemistry, Vol. 278, Issue 45, pp. 44255-64, (2003) (PubMed).
: "Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 15601-6, (2003) (PubMed).
: "Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300." in: Genes & development, Vol. 9, Issue 10, pp. 1188-98, (1995) (PubMed).
Synonyme und alternative Namen zu p107
retinoblastoma-like 1 L homeolog (rbl1.L), RB transcriptional corepressor like 1 (RBL1), retinoblastoma-like 1 (p107) (rbl1), retinoblastoma-like 1 (rbl1), retinoblastoma-like 1 (p107) (RBL1), RB transcriptional corepressor like 1 (rbl1), retinoblastoma-like 1 (p107) (Rbl1), RB transcriptional corepressor like 1 (Rbl1), AW547426, CP107, fj58e06, p107, prb1, PRB1, wu:fj58e06Bezeichner auf Proteinebene für p107
- retinoblastoma-like 1 (p107)
- retinoblastoma-like protein 1
- retinoblastoma-like protein 1-like
- 107 kDa retinoblastoma-associated protein
- cellular protein 107
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