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P2RX7 Produkte

(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Kategorien

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010].

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Ausgewählte P2RX7 Kategorien

P2RX7 Antikörper

High quality antibodies with extensive validation data.

P2RX7 ELISA Kits

Reliable ELISA kits for a wide range of species.

P2RX7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene P2RX7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, FACS, ICC
Validierungen
  • (6)
Kat. Nr. ABIN5542663
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN2855803
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN651861
Menge 400 μL
Datenblatt Datenblatt

Empfohlene P2RX7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969783
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958994
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1146777
Menge 96 tests
Datenblatt Datenblatt

Empfohlene P2RX7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7491711
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313816
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN6964308
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren P2RX7 Produkten

Xiao, Li, Zhang, Xu, Zhang: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." in: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).

Gilbert, Oliphant, Hassan, Peille, Bronsert, Falzoni, Di Virgilio, McNulty, Lara: "ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival." in: Oncogene, Vol. 38, Issue 2, pp. 194-208, (2019) (PubMed).

Felix, Teng, Bates, Ma, Jaimez, Sleiman, Tran, Wu: "P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response." in: Frontiers in immunology, Vol. 10, pp. 411, (2019) (PubMed).

Martin, Amar, Dalle, Youssef, Boucher, Le Duigou, Brückner, Prigent, Sazdovitch, Halle, Kanellopoulos, Fontaine, Delatour, Delarasse: "New role of P2X7 receptor in an Alzheimer's disease mouse model." in: Molecular psychiatry, Vol. 24, Issue 1, pp. 108-125, (2019) (PubMed).

Yoshizawa, Bi, Keskin, Zhang, Reinhold, Reinherz: "TCR-pMHC encounter differentially regulates transcriptomes of tissue-resident CD8 T cells." in: European journal of immunology, Vol. 48, Issue 1, pp. 128-150, (2018) (PubMed).

Zhou, Tan, Mo, Gao, He, Li, Huang, Li, Guo, Guo, Wang, Yang, Zhang: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).

Huang, Walker, Pennock, Else, Muller, Daniels, Pellegrini, Brough, Lopez-Castejon, Cruickshank: "P2X7 receptor-dependent tuning of gut epithelial responses to infection." in: Immunology and cell biology, Vol. 95, Issue 2, pp. 178-188, (2016) (PubMed).

Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." in: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, (2015) (PubMed).

Deng, Guo, Yuan, Shang, Zhu, Liu: "P2X7 Receptor Antagonism Attenuates the Intermittent Hypoxia-induced Spatial Deficits in a Murine Model of Sleep Apnea Via Inhibiting Neuroinflammation and Oxidative Stress." in: Chinese medical journal, Vol. 128, Issue 16, pp. 2168-75, (2015) (PubMed).

Okura, Horishita, Ueno, Yanagihara, Sudo, Uezono, Minami, Kawasaki, Sata: "Lidocaine preferentially inhibits the function of purinergic P2X7 receptors expressed in Xenopus oocytes." in: Anesthesia and analgesia, Vol. 120, Issue 3, pp. 597-605, (2015) (PubMed).

Synonyme und alternative Namen zu P2RX7

purinergic receptor P2X 7 (P2RX7), purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7), P2X purinoceptor 7 (LOC100458463), purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7), purinergic receptor P2X 7 (P2rx7), AI467586, P2RX7, P2X(7), P2X7, p2x7, P2X7R, p2xr7

Bezeichner auf Proteinebene für P2RX7

  • P2X purinoceptor 7
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • p2X purinoceptor 7-like
  • ATP receptor
  • P2X7 receptor
  • P2Z receptor
  • purinergic receptor P2X7 variant A
  • P2X7 purinoceptor
  • purinergic receptor P2X7
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