p300 Produkte
(E1A Binding Protein P300 (EP300))
Kategorien
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008].
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Ausgewählte p300 Kategorien
p300 Antikörper
High quality antibodies with extensive validation data.
p300 ELISA Kits
Reliable ELISA kits for a wide range of species.
p300 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene p300 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN6140193
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN560748
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN3042372
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene p300 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955487
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955486
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955488
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene p300 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352865
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN2669637
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2720219
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren p300 Produkten
: "Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions." in: Molecular cell, Vol. 71, Issue 5, pp. 718-732.e9, (2019) (PubMed).: "MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes." in: Molecular cell, Vol. 70, Issue 5, pp. 825-841.e6, (2018) (PubMed).
: "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway." in: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018) (PubMed).
: "miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy." in: Diabetes, Vol. 65, Issue 3, pp. 768-79, (2016) (PubMed).
: "Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions." in: Scientific reports, Vol. 6, pp. 29311, (2016) (PubMed).
: "PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia." in: Oncotarget, Vol. 7, Issue 6, pp. 6379-97, (2016) (PubMed).
: "An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility." in: Biological psychiatry, Vol. 80, Issue 12, pp. 943-954, (2016) (PubMed).
: "A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer." in: Oncotarget, Vol. 7, Issue 6, pp. 7253-67, (2016) (PubMed).
: "The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway." in: Biochemical pharmacology, Vol. 101, pp. 100-11, (2016) (PubMed).
: "Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120352, (2015) (PubMed).
Synonyme und alternative Namen zu p300
E1A binding protein p300 (EP300), histone acetyltransferase p300 (LOC446056), E1A binding protein p300 (ep300), E1A binding protein p300 (Ep300), A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2Bezeichner auf Proteinebene für p300
- histone acetyltransferase p300
- histone acetyltransferase
- E1A binding protein p300
- histone acetyltransferase p300-like
- E1A-associated protein p300
- E1A-binding protein, 300kD
- p300 HAT
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