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p300 Produkte

(E1A Binding Protein P300 (EP300))
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008].

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Ausgewählte p300 Kategorien

p300 Antikörper

High quality antibodies with extensive validation data.

p300 ELISA Kits

Reliable ELISA kits for a wide range of species.

p300 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene p300 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN6140193
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN560748
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN3042372
Menge 100 μg
Datenblatt Datenblatt

Empfohlene p300 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955487
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955486
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955488
Menge 96 tests
Datenblatt Datenblatt

Empfohlene p300 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352865
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN2669637
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2720219
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren p300 Produkten

Latorre-Muro, Baeza, Armstrong, Hurtado-Guerrero, Corzana, Wu, Sinclair, López-Buesa, Carrodeguas, Denu: "Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions." in: Molecular cell, Vol. 71, Issue 5, pp. 718-732.e9, (2019) (PubMed).

Dhar, Zhao, Lin, Gu, Pal, Wu, Alam, Lv, Yun, Gopalakrishnan, Flores, Northcott, Rajaram, Li, Shilatifard, Sillitoe, Chen, Lee: "MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes." in: Molecular cell, Vol. 70, Issue 5, pp. 825-841.e6, (2018) (PubMed).

Xiao, Ye, Zhou, Huang, Liu, Huang, Zhu, Wu, Zhang, Cai: "Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway." in: Archives of biochemistry and biophysics, Vol. 640, pp. 37-46, (2018) (PubMed).

Feng, Cao, Chen, Chu, Chu, Chakrabarti: "miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy." in: Diabetes, Vol. 65, Issue 3, pp. 768-79, (2016) (PubMed).

Lee, Huang, Chang, Huang, Hsieh, Chen, Chou, Chiang, Lai, Shiau: "Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions." in: Scientific reports, Vol. 6, pp. 29311, (2016) (PubMed).

Luo, Chen, Chen, Alkam, Wang, Semenza: "PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia." in: Oncotarget, Vol. 7, Issue 6, pp. 6379-97, (2016) (PubMed).

Martinez, Abe, Hong, Molyneux, Yarnell, Löhr, Driever, Acosta, Arcos-Burgos, Muenke: "An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility." in: Biological psychiatry, Vol. 80, Issue 12, pp. 943-954, (2016) (PubMed).

Paladino, Yue, Furuya, Acoba, Rosser, Turkson: "A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer." in: Oncotarget, Vol. 7, Issue 6, pp. 7253-67, (2016) (PubMed).

Zhang, Zhang, Xiao, Liu, Wang, Gao, Rong, Yao, Li, Xu: "The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway." in: Biochemical pharmacology, Vol. 101, pp. 100-11, (2016) (PubMed).

Aubry, Shin, Crary, Lefort, Qureshi, Lefebvre, Califano, Shelanski: "Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120352, (2015) (PubMed).

Synonyme und alternative Namen zu p300

E1A binding protein p300 (EP300), histone acetyltransferase p300 (LOC446056), E1A binding protein p300 (ep300), E1A binding protein p300 (Ep300), A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2

Bezeichner auf Proteinebene für p300

  • histone acetyltransferase p300
  • histone acetyltransferase
  • E1A binding protein p300
  • histone acetyltransferase p300-like
  • E1A-associated protein p300
  • E1A-binding protein, 300kD
  • p300 HAT
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