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P4HA1 Produkte

(Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))

Kategorien

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte P4HA1 Kategorien

P4HA1 Antikörper

High quality antibodies with extensive validation data.

P4HA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

P4HA1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene P4HA1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN190847
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7164781
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN518574
Menge 50 μg
Datenblatt Datenblatt

Empfohlene P4HA1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969620
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969621
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958833
Menge 96 tests
Datenblatt Datenblatt

Empfohlene P4HA1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124598
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313832
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7397948
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren P4HA1 Produkten

Islam, Fossum, Hansen, Urbarova, Knutsen, Martinez-Zubiaurre: "In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes." in: BMC musculoskeletal disorders, Vol. 20, Issue 1, pp. 19, (2019) (PubMed).

Xiang, Gilkes, Hu, Takano, Luo, Lu, Bullen, Samanta, Liang, Semenza: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).

Xiang, Gilkes, Chaturvedi, Luo, Hu, Takano, Liang, Semenza: "Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 2, pp. 151-64, (2014) (PubMed).

Cowling, Yeo, Kim, Park, Gu, Dalton, Peterson, Greenberg: "Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse." in: American journal of physiology. Heart and circulatory physiology, Vol. 307, Issue 5, pp. H773-81, (2014) (PubMed).

Gilkes, Bajpai, Chaturvedi, Wirtz, Semenza: "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10819-29, (2013) (PubMed).

Gilkes, Chaturvedi, Bajpai, Wong, Wei, Pitcairn, Hubbi, Wirtz, Semenza: "Collagen prolyl hydroxylases are essential for breast cancer metastasis." in: Cancer research, Vol. 73, Issue 11, pp. 3285-96, (2013) (PubMed).

Ishikura-Kinoshita, Saeki, Tsuji-Naito: "BBF2H7-mediated Sec23A pathway is required for endoplasmic reticulum-to-Golgi trafficking in dermal fibroblasts to promote collagen synthesis." in: The Journal of investigative dermatology, Vol. 132, Issue 8, pp. 2010-8, (2012) (PubMed).

Ma, Guo, Liu, Liu, Hu, Sun, Yu, Lammi: "Proteomic changes in articular cartilage of human endemic osteoarthritis in China." in: Proteomics, Vol. 11, Issue 14, pp. 2881-90, (2011) (PubMed).

Wu, So, Davis-Dusenbery, Qi, Bloch, Shi, Lagna, Hata: "Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2." in: Molecular and cellular biology, Vol. 31, Issue 23, pp. 4760-74, (2011) (PubMed).

Van Duyn Graham, Sweetwyne, Pallero, Murphy-Ullrich: "Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7067-78, (2010) (PubMed).

Synonyme und alternative Namen zu P4HA1

prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ000975), prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ017131), prolyl 4-hydroxylase subunit alpha-1 (Tsp_03346), prolyl 4-hydroxylase subunit alpha-1 (Tsp_03347), prolyl 4-hydroxylase subunit alpha-1 (Tsp_15957), prolyl 4-hydroxylase subunit alpha 1 (P4HA1), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (P4ha1), prolyl 4-hydroxylase subunit alpha 1 (P4ha1), AL022634, P4HA, P4ha, PHalphaI

Bezeichner auf Proteinebene für P4HA1

  • prolyl 4-hydroxylase subunit alpha-1
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I
  • prolyl 4-hydroxylase alpha subunit
  • prolyl 4-hydroxylase, alpha I subunit
  • 4-PH alpha-1
  • procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1
  • C-P4Halpha(I)
  • collagen prolyl 4-hydroxylase alpha(I)
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
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