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PCSK1 Produkte

(Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010].

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Ausgewählte PCSK1 Kategorien

PCSK1 Antikörper

High quality antibodies with extensive validation data.

PCSK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PCSK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PCSK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
  • (7)
Kat. Nr. ABIN7435748
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7443446
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IF
Validierungen
  • (8)
Kat. Nr. ABIN562137
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PCSK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958849
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958850
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1571753
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PCSK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314348
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7406851
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN1989721
Menge 25 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PCSK1 Produkten

Evans, Rodriguez, Ragolia: "ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling." in: Cell and tissue research, Vol. 352, Issue 2, pp. 413-25, (2013) (PubMed).

Evans, Fernando, Ragolia: "Functional melanocortin-2 receptors are expressed by mouse aorta-derived mesenchymal progenitor cells." in: Molecular and cellular endocrinology, Vol. 355, Issue 1, pp. 60-70, (2012) (PubMed).

Mbikay, Sirois, Nkongolo, Basak, Chrétien: "Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity." in: Molecular genetics and metabolism, Vol. 104, Issue 4, pp. 682-7, (2011) (PubMed).

Jackson, Creemers, Farooqi, Raffin-Sanson, Varro, Dockray, Holst, Brubaker, Corvol, Polonsky, Ostrega, Becker, Bertagna, Hutton, White, Dattani, Hussain, Middleton, Nicole, Milla, Lindley, ORahilly: "Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency." in: The Journal of clinical investigation, Vol. 112, Issue 10, pp. 1550-60, (2003) (PubMed).

Synonyme und alternative Namen zu PCSK1

proprotein convertase subtilisin/kexin type 1 (PCSK1), proprotein convertase subtilisin/kexin type 1 (Pcsk1), proprotein convertase subtilisin/kexin type 1 (pcsk1), prohormone convertase 1 (PC1B), BDP, BMIQ12, Nec-1, NEC1, Nec1, PC1, PC1/3, PC3, Phpp-1, SPC3

Bezeichner auf Proteinebene für PCSK1

  • NEC 1
  • neuroendocrine convertase 1
  • prohormone convertase 1
  • prohormone convertase 3
  • furin homolog
  • prohormone convertase 1/3
  • propeptide-processing protease
  • proprotein convertase 1
  • Protein convertase subtilisin / kexin type I
  • Protein convertase subtilisin / kexin, type I
  • prohormone convertase
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