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PCSK6 Produkte

(Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Kategorien

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Ausgewählte PCSK6 Kategorien

PCSK6 Antikörper

High quality antibodies with extensive validation data.

Empfohlene PCSK6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN562089
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN308447
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cow, Horse, Human, Monkey, Rabbit, Rat
Applikation ELISA, IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN461695
Menge 50 μg
Datenblatt Datenblatt

Empfohlene PCSK6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958854
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PCSK6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314361
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PCSK6 Produkten

Ha, Jin, Jorgensen, Zogg, Wei, Singh, Park, Kurahashi, Kim, Baek, Poudrier, Lee, Sanders, Ro: "Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers." in: PloS one, Vol. 17, Issue 5, pp. e0261743, (2022) (PubMed).

Perisic, Hedin, Razuvaev, Lengquist, Osterholm, Folkersen, Gillgren, Paulsson-Berne, Ponten, Odeberg, Hedin: "Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, Issue 10, pp. 2432-43, (2013) (PubMed).

Jin, Wang, Millar, Quertermous, Rothblat, Glick, Rader: "Hepatic proprotein convertases modulate HDL metabolism." in: Cell metabolism, Vol. 6, Issue 2, pp. 129-36, (2007) (PubMed).

Klee, Finlay, McDonald, Attewell, Hebrink, Dyer, Love, Vasmatzis, Li, Beechem, Klee: "Bioinformatics methods for prioritizing serum biomarker candidates." in: Clinical chemistry, Vol. 52, Issue 11, pp. 2162-4, (2007) (PubMed).

Khatib, Siegfried, Chrétien, Metrakos, Seidah: "Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy." in: The American journal of pathology, Vol. 160, Issue 6, pp. 1921-35, (2002) (PubMed).

Synonyme und alternative Namen zu PCSK6

proprotein convertase subtilisin/kexin type 6 (PCSK6), peptidase S8 (EAMY_RS27925), proprotein convertase subtilisin/kexin type 6 (pcsk6), proprotein convertase subtilisin/kexin type 6 (Pcsk6), proprotein convertase subtilisin/kexin type 6 L homeolog (pcsk6.L), C86343, PACE4, Pace4, PACE4AIIa, PCSK6, SPC4, Spc4, spc4, Xpace4

Bezeichner auf Proteinebene für PCSK6

  • proprotein convertase PACE4
  • proprotein convertase subtilisin/kexin type 6
  • proprotein convertase subtilisin/kexin type 6-like
  • paired basic amino acid cleaving enzyme 4
  • paired basic amino acid cleaving system 4
  • subtilisin-like proprotein convertase 4
  • subtilisin/kexin-like protease PACE4
  • Subtilisin - like endoprotease
  • kexin-like protease PC7A
  • subtilisin-like kinase SPC4
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