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PCSK9 Produkte

(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008].

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Ausgewählte PCSK9 Kategorien

PCSK9 Antikörper

High quality antibodies with extensive validation data.

PCSK9 ELISA Kits

Reliable ELISA kits for a wide range of species.

PCSK9 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PCSK9 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (7)
Kat. Nr. ABIN652320
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (6)
Kat. Nr. ABIN6145328
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7427117
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PCSK9 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6962331
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6963307
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6973907
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PCSK9 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7275415
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275416
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (10)
  • (3)
Kat. Nr. ABIN2181580
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PCSK9 Produkten

Wang, Amiss, Weidmann, Craik: "Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery." in: The Journal of biological chemistry, Vol. 295, Issue 34, pp. 12143-12152, (2021) (PubMed).

Burnap, Sattler, Pechlaner, Duregotti, Lu, Theofilatos, Takov, Heusch, Tsimikas, Fernandez-Hernando, Berry, Hall, Notdurfter, Rungger, Paulweber, Willeit, Kiechl, Levkau, Mayr: "PCSK9 Activity Is Potentiated Through HDL Binding." in: Circulation research, (2021) (PubMed).

Grzegorczyk, Książek, Kurek, Łukaszuk, Rosołowski, Paszko, Krzyżak, Żendzian-Piotrowska: "Effect of Sleeve Gastrectomy on Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) Content and Lipid Metabolism in the Blood Plasma and Liver of Obese Wistar Rats." in: Nutrients, Vol. 11, Issue 9, (2020) (PubMed).

Dalgic, Abaci, Kocas, Cetinkal, Dalgic, Buyuk, Ser, Batit, Arat, Gurmen: "The relationship between protein convertase subtilisin kexin type-9 levels and extent of coronary artery disease in patients with non-ST-elevation myocardial infarction." in: Coronary artery disease, Vol. 31, Issue 1, pp. 81-86, (2020) (PubMed).

Lebeau, Platko, Al-Hashimi, Byun, Lhoták, Holzapfel, Gyulay, Igdoura, Cool, Trigatti, Seidah, Austin: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).

Elseweidy, Amin, Atteia, El-Zeiky, Al-Gabri et al.: "New Insight on a Combination of Policosanol and 10-Dehydrogingerdione Phytochemicals as Inhibitors for Platelet Activation Biomarkers and Atherogenicity Risk in Dyslipidemic Rabbits: Role of CETP and ..." in: Applied biochemistry and biotechnology, Vol. 186, Issue 4, pp. 805-815, (2019) (PubMed).

El-Seweidy, Sarhan Amin, Husseini Atteia, El-Zeiky, Al-Gabri: "Dyslipidemia induced inflammatory status, platelet activation and endothelial dysfunction in rabbits: Protective role of 10-Dehydrogingerdione." in: Biomedicine & pharmacotherapy, Vol. 110, pp. 456-464, (2019) (PubMed).

Chen, Lichtor, Berliner, Chen, Liu: "Evolution of sequence-defined highly functionalized nucleic acid polymers." in: Nature chemistry, Vol. 10, Issue 4, pp. 420-427, (2019) (PubMed).

Lichtor, Chen, Elowe, Chen, Liu: "Side chain determinants of biopolymer function during selection and replication." in: Nature chemical biology, Vol. 15, Issue 4, pp. 419-426, (2019) (PubMed).

Wijers, Zanoni, Liv, Vos, Jäckstein, Smit, Wilbrink, Wolters, van der Veen, Huijkman, Dekker, Kloosterhuis, van Dijk, Billadeau, Kuipers, Klumperman, von Eckardstein, Kuivenhoven, van de Sluis: "The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance." in: JCI insight, Vol. 4, Issue 11, (2019) (PubMed).

Synonyme und alternative Namen zu PCSK9

proprotein convertase subtilisin/kexin type 9 (PCSK9), proprotein convertase subtilisin/kexin type 9 L homeolog (pcsk9.L), proprotein convertase subtilisin/kexin type 9 (pcsk9), proprotein convertase subtilisin/kexin type 9 (Pcsk9), AI415265, AI747682, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, Narc1, PC9

Bezeichner auf Proteinebene für PCSK9

  • convertase subtilisin/kexin type 9 preproprotein
  • neural apoptosis regulated convertase 1
  • subtilisin/kexin-like protease PC9
  • proprotein convertase 9
  • proprotein convertase PC9
  • proprotein convertase subtilisin/kexin type 9
  • proprotein convertase subtilisin/kexin type 9 preproprotein
  • NARC-1
  • convertase subtilisin
  • neural apoptosis-regulated convertase 1
  • Proprotein convertase 9
  • Subtilisin/kexin-like protease PC9
  • LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9
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