PDE10A Produkte
(phosphodiesterase 10A (PDE10A))
Kategorien
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011].
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Ausgewählte PDE10A Kategorien
PDE10A Antikörper
High quality antibodies with extensive validation data.
PDE10A ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE10A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE10A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN2728471
Menge
0.1 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7436099
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, ICC, IF
Validierungen
- (2)
Kat. Nr.
ABIN6264085
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE10A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969258
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958527
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN456476
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE10A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314446
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7398554
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136395
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE10A Produkten
: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).: "Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161035, (2016) (PubMed).
: "Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity." in: Oncogene, Vol. 34, Issue 12, pp. 1499-509, (2015) (PubMed).
: "Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A." in: Nuclear medicine and biology, Vol. 42, Issue 2, pp. 146-54, (2015) (PubMed).
: "Levodopa-induced dyskinesias are associated with transient down-regulation of cAMP and cGMP in the caudate-putamen of hemiparkinsonian rats: reduced synthesis or increased catabolism?" in: Neurochemistry international, Vol. 79, pp. 44-56, (2015) (PubMed).
: "Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions." in: Neuropharmacology, Vol. 76 Pt A, pp. 127-36, (2014) (PubMed).
: "Phosphodiesterase 2 inhibitors promote axonal outgrowth in organotypic slice co-cultures." in: Neuro-Signals, Vol. 21, Issue 3-4, pp. 197-212, (2013) (PubMed).
: "Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling." in: PLoS ONE, Vol. 6, Issue 4, pp. e18136, (2011) (PubMed).
: "PDE10A and PDE10A-dependent cAMP catabolism are dysregulated oppositely in striatum and nucleus accumbens after lesion of midbrain dopamine neurons in rat: a key step in parkinsonism physiopathology." in: Neurobiology of disease, Vol. 43, Issue 1, pp. 293-303, (2011) (PubMed).
: "The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release." in: British journal of pharmacology, Vol. 157, Issue 4, pp. 633-44, (2009) (PubMed).
Synonyme und alternative Namen zu PDE10A
phosphodiesterase 10A (PDE10A), phosphodiesterase 10A (Pde10a), HSPDE10A, Pde10a3Bezeichner auf Proteinebene für PDE10A
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
- dJ416F21.1 (phosphodiesterase 10A)
- phosphodiesterase 10A1 (PDE10A1)
- PDE10A2 brain-specific isoform
- dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase
- testis-specific phosphodiesterase PDE10A2
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