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PDE11A Produkte

(phosphodiesterase 11A (PDE11A))

Kategorien

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte PDE11A Kategorien

PDE11A Antikörper

High quality antibodies with extensive validation data.

PDE11A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDE11A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7150681
Menge 100 μg
Datenblatt Datenblatt

Applikation IHC, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN213553
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (2)
Kat. Nr. ABIN7269298
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PDE11A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3094408
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3132723
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2728475
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDE11A Produkten

Kelly: "Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?" in: Current pharmaceutical design, Vol. 21, Issue 3, pp. 389-416, (2015) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Kelly, Adamowicz, Bove, Hartman, Mariga, Pathak, Reinhart, Romegialli, Kleiman: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).

Hamilton, Hu, Kolomitro, Bell, Maurice, Graham, Siemens: "Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer." in: World journal of urology, Vol. 31, Issue 2, pp. 325-30, (2013) (PubMed).

Ückert, Oelke, Albrecht, Breitmeier, Kuczyk, Hedlund: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." in: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).

Ückert, Waldkirch, Sonnenberg, Sandner, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Peverelli, Ermetici, Filopanti, Elli, Ronchi, Mantovani, Ferrero, Bosari, Beck-Peccoz, Lania, Spada: "Analysis of genetic variants of phosphodiesterase 11A in acromegalic patients." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 5, pp. 687-94, (2009) (PubMed).

Kruse, Møller, Tibaek, Gammeltoft, Olesen, Kruuse: "PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system." in: Brain research, Vol. 1281, pp. 25-34, (2009) (PubMed).

Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." in: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

Synonyme und alternative Namen zu PDE11A

phosphodiesterase 11A (PDE11A), phosphodiesterase 11A (Pde11a), phosphodiesterase 11a (pde11a), phosphodiesterase 11A (pde11a), dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (LOC100470038), dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Pde11a), 6330414F14Rik, A630086N24Rik, Gm350, PDE11A, Pde11a, PDE11A1, PPNAD2, ppnad2, si:ch211-222f23.5

Bezeichner auf Proteinebene für PDE11A

  • cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
  • dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
  • cAMP and cGMP phosphodiesterase 11A
  • phosphodiesterase 11A
  • dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like
  • phosphodiesterase 11a
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