PDE3A Produkte
(phosphodiesterase 3A, cGMP-Inhibited (PDE3A))
Kategorien
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
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Ausgewählte PDE3A Kategorien
PDE3A Antikörper
High quality antibodies with extensive validation data.
PDE3A ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE3A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE3A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7259753
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN518720
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7269301
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE3A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958531
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5674894
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5674895
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE3A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314458
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408213
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3114834
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE3A Produkten
: "Possible mechanisms mediating the protective effect of cilostazol in L-arginine induced acute pancreatitis in rats: role of cGMP, cAMP, and HO-1." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 10, pp. 1859-1870, (2020) (PubMed).: "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." in: Cellular signalling, Vol. 28, Issue 7, pp. 725-32, (2017) (PubMed).
: "The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway." in: Science signaling, Vol. 8, Issue 398, pp. ra101, (2016) (PubMed).
: "Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly. ..." in: Hypertension (Dallas, Tex. : 1979), Vol. 66, Issue 4, pp. 800-8, (2015) (PubMed).
: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).
: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).
: "Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 2, pp. 388-400, (2012) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).
Synonyme und alternative Namen zu PDE3A
phosphodiesterase 3A (PDE3A), phosphodiesterase 3A, cGMP-inhibited (Pde3a), cGMP-inhibited 3',5'-cyclic phosphodiesterase A (LOC100540515), phosphodiesterase 3A (pde3a), phosphodiesterase 3A, cGMP-inhibited (pde3a), phosphodiesterase 3A, cGMP inhibited (Pde3a), phosphodiesterase 3A (Pde3a), A930022O17Rik, C87899, CGI-PDE, CGI-PDE-A, CGI-PDE A, PDE3A, Pde3a, RNPDE3A, si:dkey-48h7.2Bezeichner auf Proteinebene für PDE3A
- phosphodiesterase 3A, cGMP-inhibited
- cGMP-inhibited 3',5'-cyclic phosphodiesterase A
- phosphodiesterase 3a
- cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like
- CGI-PDE A
- cGMP-inhibited phosphodiesterase
- cyclic GMP-inhibited phosphodiesterase A
- cyclic nucleotide phosphodiesterase
- cAMP phosphodiesterase, myocardial cGMP-inhibited
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