PDE5A Produkte
(phosphodiesterase 5A, cGMP-Specific (PDE5A))
Kategorien
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte PDE5A Kategorien
PDE5A Antikörper
High quality antibodies with extensive validation data.
PDE5A ELISA Kits
Reliable ELISA kits for a wide range of species.
PDE5A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE5A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN563735
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, FACS
Validierungen
- (4)
Kat. Nr.
ABIN185350
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB, IHC
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN2789423
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE5A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969266
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969265
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958535
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE5A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314473
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7414600
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136441
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE5A Produkten
: "Novel effect of sildenafil on hair growth." in: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 685-691, (2018) (PubMed).: "PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease." in: Journal of Alzheimer's disease : JAD, Vol. 52, Issue 1, pp. 295-302, (2016) (PubMed).
: "Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 9, pp. 2271-82, (2016) (PubMed).
: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).
: "Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A." in: PLoS ONE, Vol. 9, Issue 9, pp. e107627, (2015) (PubMed).
: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." in: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, (2015) (PubMed).
: "Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy." in: Annals of neurology, Vol. 76, Issue 4, pp. 550-7, (2014) (PubMed).
: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." in: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).
Synonyme und alternative Namen zu PDE5A
phosphodiesterase 5A (PDE5A), phosphodiesterase 5A (Pde5a), phosphodiesterase 5A, cGMP-specific (Pde5a), phosphodiesterase 5A S homeolog (pde5a.S), phosphodiesterase 5A, cGMP-specific, b (pde5ab), phosphodiesterase 5A (pde5a), CGB-PDE, cgb-pde, Cgbpde, CN5A, cn5a, Cn5n, PDE5, Pde5, pde5, PDE5A, pde5a, Pde5a1, pde5a1, PDE5A2Bezeichner auf Proteinebene für PDE5A
- cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase
- cGMP-specific 3',5'-cyclic phosphodiesterase
- cGMP-specific phosphodiesterase PDE5A2
- cGMP-specific phosphodiesterase type 5A
- phosphodiesterase isozyme 5
- CGB-PDE
- cGMP-binding cGMP specific phosphodiesterase 5A2
- cGMP-binding cGMP-specific phosphodiesterase
- phosphodiesterase type 5
- cGMP-binding/cGMP-specific phosphodiesterase
- 3',5'-Cyclic GMP Phosphodiesterase
- phosphodiesterase 5A, cGMP-specific
- phosphodiesterase 5a, cGMP-specific
- phosphodiesterase 5a
- cGMP-specific 3',5'-cyclic phosphodiesterase-like
- cyclic nucleotide phosphodiesterase 5a
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