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PDE8B Produkte

(phosphodiesterase 8B (PDE8B))

Kategorien

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010].

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Ausgewählte PDE8B Kategorien

PDE8B Antikörper

High quality antibodies with extensive validation data.

Empfohlene PDE8B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1881646
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Bat, Horse, Human, Monkey
Applikation IHC (p), IHC
Validierungen
  • (2)
Kat. Nr. ABIN213535
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF
Validierungen
  • (1)
Kat. Nr. ABIN7155168
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PDE8B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3094523
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3131150
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDE8B Produkten

Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).

Shields, Freathy, Knight, Hill, Weedon, Frayling, Hattersley, Vaidya: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).

Bimpaki, Nesterova, Stratakis: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).

Horvath, Giatzakis, Tsang, Greene, Osorio, Boikos, Libè, Patronas, Robinson-White, Remmers, Bertherat, Nesterova, Stratakis: "A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex." in: European journal of human genetics : EJHG, Vol. 16, Issue 10, pp. 1245-53, (2008) (PubMed).

Synonyme und alternative Namen zu PDE8B

phosphodiesterase 8B (PDE8B), high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (LOC100468338), phosphodiesterase 8B (pde8b), phosphodiesterase 8B (Pde8b), ADSD, B230331L10Rik, C030047E14Rik, PDE8B, PPNAD3, RNPDE8B

Bezeichner auf Proteinebene für PDE8B

  • phosphodiesterase 8B
  • high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like
  • 3',5' cyclic nucleotide phosphodiesterase 8B
  • cell proliferation-inducing gene 22 protein
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • hsPDE8B
  • cAMP-specific cyclic nucleotide phosphodiesterase PDE8
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