PDE8B Produkte
(phosphodiesterase 8B (PDE8B))
Kategorien
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010].
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Ausgewählte PDE8B Kategorien
PDE8B Antikörper
High quality antibodies with extensive validation data.
Empfohlene PDE8B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1881646
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Bat, Horse, Human, Monkey
Applikation
IHC (p), IHC
Validierungen
- (2)
Kat. Nr.
ABIN213535
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF
Validierungen
- (1)
Kat. Nr.
ABIN7155168
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE8B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094523
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131150
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE8B Produkten
: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).
: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).
: "A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex." in: European journal of human genetics : EJHG, Vol. 16, Issue 10, pp. 1245-53, (2008) (PubMed).
Synonyme und alternative Namen zu PDE8B
phosphodiesterase 8B (PDE8B), high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (LOC100468338), phosphodiesterase 8B (pde8b), phosphodiesterase 8B (Pde8b), ADSD, B230331L10Rik, C030047E14Rik, PDE8B, PPNAD3, RNPDE8BBezeichner auf Proteinebene für PDE8B
- phosphodiesterase 8B
- high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
- high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like
- 3',5' cyclic nucleotide phosphodiesterase 8B
- cell proliferation-inducing gene 22 protein
- high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
- hsPDE8B
- cAMP-specific cyclic nucleotide phosphodiesterase PDE8
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