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PDGFRA Produkte

(Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Kategorien

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].

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Ausgewählte PDGFRA Kategorien

PDGFRA Antikörper

High quality antibodies with extensive validation data.

PDGFRA ELISA Kits

Reliable ELISA kits for a wide range of species.

PDGFRA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDGFRA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
  • (2)
  • (6)
Kat. Nr. ABIN5611263
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN392024
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, ICC
Validierungen
  • (5)
Kat. Nr. ABIN5542490
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene PDGFRA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (6)
Kat. Nr. ABIN6720580
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969416
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969415
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PDGFRA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275439
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275438
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275440
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDGFRA Produkten

Bychkov, Kirichenko, Mikhaylova, Paramonov, Yastremsky, Kirpichnikov, Shulepko, Lyukmanova: "Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal Keratinocytes." in: , Vol. 10, Issue 3, (2022) (PubMed).

Bychkov, Shulepko, Shlepova, Kulbatskii, Chulina, Paramonov, Baidakova, Azev, Koshelev, Kirpichnikov, Shenkarev, Lyukmanova: "SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer." in: Frontiers in cell and developmental biology, Vol. 9, pp. 739391, (2021) (PubMed).

Stringer, Day, DSouza, Jamieson, Ensbey, Bruce, Lim, Goasdoué, Offenhäuser, Akgül, Allan, Robertson, Lucas, Tollesson, Campbell, Winter, Do, Dobrovic, Inglis, Jeffree, Johns, Boyd: "A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma." in: Scientific reports, Vol. 9, Issue 1, pp. 4902, (2019) (PubMed).

Szubert, Moszynski, Szpurek, Romaniuk, Sajdak, Nowicki, Michalak: "The expression of Platelet-derived Growth factor receptors (PDGFRs) and their correlation with overall survival of patients with ovarian cancer." in: Ginekologia polska, Vol. 90, Issue 5, pp. 242-249, (2019) (PubMed).

Suehara, Alex, Bowman, Middha, Zehir, Chakravarty, Wang, Jour, Nafa, Hayashi, Jungbluth, Frosina, Slotkin, Shukla, Meyers, Healey, Hameed, Ladanyi: "Clinical genomic sequencing of pediatric and adult osteosarcoma reveals distinct molecular subsets with potentially targetable alterations." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2019) (PubMed).

Nance, Shi, Hakim, Wasala, Yue, Pan, Zhang, Robinson, Duan, Yao, Yang, Chen, Wagner, Gersbach, Duan: "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 9, pp. 1568-1585, (2019) (PubMed).

Yoon, Wu, Armstrong, Habib, Rossi: "An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 131-141, (2019) (PubMed).

Min, Jaichander, Sanchez-Ortiz, Bezprozvannaya, Malladi, Cui, Wang, Bassel-Duby, Olson, Liu: "Identification of a multipotent Twist2-expressing cell population in the adult heart." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 36, pp. E8430-E8439, (2018) (PubMed).

Stegmann, Hochdorfer, Lieber, Subramanian, Stöhr, Laib Sampaio, Sinzger: "A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells." in: PLoS pathogens, Vol. 13, Issue 4, pp. e1006273, (2017) (PubMed).

Lee, Protze, Laksman, Backx, Keller: "Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations." in: Cell stem cell, Vol. 21, Issue 2, pp. 179-194.e4, (2017) (PubMed).

Synonyme und alternative Namen zu PDGFRA

platelet derived growth factor receptor alpha (PDGFRA), platelet derived growth factor receptor, alpha polypeptide (Pdgfra), platelet derived growth factor receptor alpha (Pdgfra), platelet-derived growth factor receptor, alpha polypeptide L homeolog (pdgfra.L), platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), AI115593, APDGFR, CD140a, CD140A, PDGFACE, PDGFR, Pdgfr-2, PDGFR-2, PDGFR-A, PDGFR2, RHEPDGFRA

Bezeichner auf Proteinebene für PDGFRA

  • platelet-derived growth factor receptor, alpha polypeptide
  • alpha-type platelet-derived growth factor receptor-like
  • Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)
  • CD140 antigen-like family member A
  • PDGF alpha chain
  • PDGF-R-alpha
  • PDGFR-alpha
  • alpha-type platelet-derived growth factor receptor
  • platelet-derived growth factor alpha receptor
  • platelet-derived growth factor receptor alpha
  • alpha platelet-derived growth factor receptor
  • CD140a antigen
  • PDGFRA/BCR fusion
  • platelet-derived growth factor receptor 2
  • rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
  • tyrosine kinase PDGFR
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