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PDK2 Produkte

(Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Kategorien

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

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Ausgewählte PDK2 Kategorien

PDK2 Antikörper

High quality antibodies with extensive validation data.

PDK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PDK2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDK2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), RNAi
Validierungen
  • (4)
  • (6)
Kat. Nr. ABIN562160
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7439423
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (5)
Kat. Nr. ABIN5542665
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PDK2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959010
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6231784
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5658317
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PDK2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314551
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314549
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509069
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDK2 Produkten

Hu, Yu, Li, Ren, Ning, Wang, Liang, Li: "PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3." in: Journal of drug targeting, Vol. 27, Issue 4, pp. 460-465, (2019) (PubMed).

Qvit, Disatnik, Sho, Mochly-Rosen: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).

Qvit, Joshi, Cunningham, Ferreira, Mochly-Rosen: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).

Le Page, Rider, Lewis, Ball, Clarke, Johansson, Carr, Heather, Tyler: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).

Hou, Zhang, Han, Ge, Ma, Zhang, Moley, Schedl, Wang: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." in: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).

Byun, Choi, Kang, Jang, Kang, Jeon, Lee, Jeon, Koo, Jeong, Harris, Lee, Park: "Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 3, pp. 953-64, (2015) (PubMed).

Hurd, Collins, Abakumova, Chouchani, Baranowski, Fearnley, Prime, Murphy, James: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, (2012) (PubMed).

Contractor, Harris: "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2." in: Cancer research, Vol. 72, Issue 2, pp. 560-7, (2012) (PubMed).

Yamasaki, Kawabe, Nakamura, Tachibana, Ishimoto, Tanaka, Aburatani, Sakai, Hamakubo, Kodama, Doi: "Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPAR?-independent mechanisms." in: European journal of cell biology, Vol. 90, Issue 8, pp. 657-64, (2011) (PubMed).

Love, LeBlanc, Inglis, Bradley, Choptiany, Heigenhauser, Peters: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, (2011) (PubMed).

Synonyme und alternative Namen zu PDK2

pyruvate dehydrogenase kinase 2 (PDK2), pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2), pyruvate dehydrogenase kinase 2 (Pdk2), pyruvate dehydrogenase kinase, isozyme 2b (pdk2b), PDHK2, Pdk, PDK2, PDKII, zgc:56209

Bezeichner auf Proteinebene für PDK2

  • PDH kinase 2
  • pyruvate dehydrogenase kinase, isoenzyme 2
  • pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
  • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial
  • pyruvate dehydrogenase 2
  • pyruvate dehydrogenase kinase, isozyme 2
  • PDK P45
  • pyruvate dehydrogenase kinase 2 subunit p45 (PDK2)
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