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PDZK1 Produkte

(PDZ Domain Containing 1 (PDZK1))
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

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Ausgewählte PDZK1 Kategorien

PDZK1 Antikörper

High quality antibodies with extensive validation data.

PDZK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PDZK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDZK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN562170
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN7269199
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN518773
Menge 200 μL
Datenblatt Datenblatt

Empfohlene PDZK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1144046
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1144047
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1144049
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PDZK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1314614
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5852951
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2131092
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDZK1 Produkten

Jansson, Venugopal, Sánchez, Magenheimer, Reif, Wallace, Calvet, Blanco: "Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells." in: The Journal of membrane biology, Vol. 248, Issue 6, pp. 1145-57, (2016) (PubMed).

Fry, Su, Yiu, Cuthbert, Trachtman, Karet Frankl: "Mutation conferring apical-targeting motif on AE1 exchanger causes autosomal dominant distal RTA." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 7, pp. 1238-49, (2012) (PubMed).

James, Brulhart-Meynet, Singh, Riederer, Seidler, Out, Van Berkel, Deakin: "The scavenger receptor class B, type I is a primary determinant of paraoxonase-1 association with high-density lipoproteins." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 11, pp. 2121-7, (2010) (PubMed).

Robichaud, Francis, Vance: "A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase." in: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35496-506, (2008) (PubMed).

Hashimoto, Suzuki, Taniguchi, Noguchi, Yohda, Odaka: "Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36617-23, (2008) (PubMed).

Walker, MacLeod, Williams, Cameron, Smyth, Langdon: "Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer." in: Gynecologic oncology, Vol. 106, Issue 3, pp. 461-8, (2007) (PubMed).

Lan, Silver: "Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23390-6, (2005) (PubMed).

Wang, Wang, Xiao, Murray, Novikoff, Angeletti, Orr, Lan, Silver, Wolkoff: "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface." in: The Journal of biological chemistry, Vol. 280, Issue 34, pp. 30143-9, (2005) (PubMed).

Synonyme und alternative Namen zu PDZK1

PDZ domain containing 1 (PDZK1), PDZ domain containing 1 L homeolog (pdzk1.L), PDZ domain containing 1 (pdzk1), PDZ domain containing 1 (Pdzk1), 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, CAP70, CLAMP, Clamp, D3Ertd537e, mPDZK1, NHERF-3, NHERF3, PDZD1, Pdzd1, PDZK1, xpdzk1

Bezeichner auf Proteinebene für PDZK1

  • PDZ domain containing 1
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF3-like
  • CFTR-associated protein of 70 kDa
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • PDZ-containing kidney protein 1
  • na/Pi cotransporter C-terminal-associated protein 1
  • naPi-Cap1
  • sodium-hydrogen exchanger regulatory factor 3
  • NHERF-3
  • Na(+)/H(+) exchanger regulatory factor 3
  • PDZ domain-containing protein 1
  • PDZK1-like protein
  • C-terminal linking and modulating protein
  • C-terminal-linking and modulating protein
  • dietary Pi-regulated RNA-1
  • diphor-1
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