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PEG10 Produkte

(Paternally Expressed 10 (PEG10))

Kategorien

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].

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Ausgewählte PEG10 Kategorien

PEG10 Antikörper

High quality antibodies with extensive validation data.

PEG10 ELISA Kits

Reliable ELISA kits for a wide range of species.

PEG10 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PEG10 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (6)
Kat. Nr. ABIN1681320
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN969348
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN524962
Menge 50 μg
Datenblatt Datenblatt

Empfohlene PEG10 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969163
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6225627
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PEG10 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314640
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3094526
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3135926
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PEG10 Produkten

Rotinen, You, Yang, Coetzee, Reis-Sobreiro, Huang, Huang, Pan, Yáñez, Hazelett, Chu, Steadman, Morrissey, Nelson, Corey, Chung, Freedland, Di Vizio, Garraway, Murali, Knudsen, Freeman: "ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis." in: Nature medicine, Vol. 24, Issue 12, pp. 1887-1898, (2019) (PubMed).

Uxa, Bernhart, Mages, Fischer, Kohler, Hoffmann, Stadler, Engeland, Müller: "DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation." in: Nucleic acids research, Vol. 47, Issue 17, pp. 9087-9103, (2019) (PubMed).

Peng, Zhu, Yin, Zhang, Wei, Liu, Liu, Gao, Jiang, Miao: "PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 30, (2017) (PubMed).

Shyu, Lee, Lu, Chen, Chien, Chen, Lin, Tsou, Chen, Hsieh, Huang: "miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma." in: Journal of translational medicine, Vol. 14, Issue 1, pp. 200, (2016) (PubMed).

Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

Synonyme und alternative Namen zu PEG10

paternally expressed 10 (PEG10), paternally expressed 10 (Peg10), AA407948, EDR, Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, RGAG3

Bezeichner auf Proteinebene für PEG10

  • MEF3 like 1
  • MEF3-like protein 1
  • embryonal carcinoma differentiation regulated
  • embryonal carcinoma differentiation-regulated protein
  • mammalian retrotransposon-derived protein 2
  • myelin expression factor 3-like protein 1
  • paternally expressed gene 10 protein
  • retrotransposon gag domain containing 3
  • retrotransposon gag domain-containing protein 3
  • retrotransposon-derived gag-like polyprotein
  • retrotransposon-derived protein PEG10
  • ty3/Gypsy-like protein
  • MyEF-3 like
  • embryonal carcinoma differentiation regulated protein
  • myelin expression factor 3
  • paternally expressed 10
  • LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
  • retrotransposon-derived protein PEG10-like
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