PEN2 Produkte
(Presenilin Enhancer 2 Homolog (PSENEN))
Kategorien
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq, Jul 2008].
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Ausgewählte PEN2 Kategorien
PEN2 Antikörper
High quality antibodies with extensive validation data.
PEN2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PEN2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PEN2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN1387540
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7139851
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN565943
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PEN2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231793
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Validierungen
Kat. Nr.
ABIN2870254
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN6200572
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PEN2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316522
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3107691
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3128357
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PEN2 Produkten
: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 7850-4, (2003) (PubMed).
: "Membrane topology of gamma-secretase component PEN-2." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 20117-23, (2003) (PubMed).
: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." in: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).
: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." in: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).
Synonyme und alternative Namen zu PEN2
presenilin enhancer gamma-secretase subunit (PSENEN), presenilin enhancer 2 (PEN2), presenilin enhancer 2 (Psenen), presenilin enhancer gamma secretase subunit (Psenen), Gamma-secretase subunit pen-2 (pen-2), presenilin enhancer (pen-2), presenilin enhancer gamma secretase subunit S homeolog (psenen.S), presenilin enhancer gamma secretase subunit (psenen), presenilin enhancer gamma-secretase subunit (Psenen), 1700023M09Rik, ACYPI006208, anon-AE003800.1, CG33198, Dmel\\CG33198, dPen-2, MSTP064, PEN-2, Pen-2, pen-2, PEN2, pen2, Psenen, psenen, RGD1312037, zgc:109727Bezeichner auf Proteinebene für PEN2
- gamma-secretase subunit PEN-2
- hematopoietic stem/progenitor cells protein MDS033
- presenilin enhancer protein 2
- presenilin enhancer 2
- LRRGT00140 mRNA
- liver regeneration-related protein LRRGT00140
- CG33198-PA
- pen-2-PA
- presenilin enhancer 2 homolog
- presenilin enhancer gamma secretase subunit S homeolog
- Presenilin enhancer protein 2 homolog
- presenilin enhancer protein 2 homolog
Haben Sie etwas anderes gesucht?
- PEMT
- PELP1
- PELO
- Pellino 3
- Pellino 1
- PELI2
- PELE
- PELB
- PELA
- Pejvakin
- PEG3
- PEG10
- PEG
- PEF1
- PEDF
- PECR
- PECI/ECI2
- PEBP4
- PEBP1
- PEBB
- Penicillin
- Penicillin G
- Penicillinase
- pepA
- PEPCK
- PEPD
- PEPPI
- Pepsin
- Pepsin A
- Pepsinogen A
- Peptidase B
- Peptidase E
- Peptide F
- Peptide Histidine-Methionine
- Peptide YY
- Peptide YY, 2 (Pseudogene)
- Peptidoglycan
- Peptidylarginine Deiminase
- Peptidylglycine alpha-Amidating Monooxygenase
- Peptidylprolyl Isomerase
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