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PERK Produkte

(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
The gene PERK, also known as EIF2AK3, plays a crucial role in cellular biology, particularly in the regulation of protein synthesis and the cellular response to stress. Dysregulation of the PERK pathway is associated with various diseases, including neurodegenerative disorders, diabetes, and cancer, making it an important target for research and potential therapeutic interventions. PERK is one of the four kinases that phosphorylate the eukaryotic translation initiation factor 2 alpha (eIF2α), which is a key component of the translation machinery in cells.

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Ausgewählte PERK Kategorien

PERK Antikörper

High quality antibodies with extensive validation data.

PERK ELISA Kits

Reliable ELISA kits for a wide range of species.

PERK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PERK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7441241
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN6255756
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Mouse, Pig, Rat
Applikation WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validierungen
  • (14)
  • (3)
Kat. Nr. ABIN744713
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PERK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966610
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966609
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955664
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PERK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352504
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5508906
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7407256
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PERK Produkten

Howley, Link, Grelet, El-Sabban, Howe: "A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer." in: Oncogene, Vol. 37, Issue 10, pp. 1308-1325, (2019) (PubMed).

Kao, Lai, Chow, Liao, Zheng, Tsai, Hsia, Lai, Lee, Chuang, Whang-Peng, Yao: "Opposite Regulation of CHOP and GRP78 and Synergistic Apoptosis Induction by Selenium Yeast and Fish Oil via AMPK Activation in Lung Adenocarcinoma Cells." in: Nutrients, Vol. 10, Issue 10, (2019) (PubMed).

Ju, Su, Chen, Ma, Ji, Wang, Li, Li: "Protective effects of Astragaloside IV on endoplasmic reticulum stress-induced renal tubular epithelial cells apoptosis in type 2 diabetic nephropathy rats." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 84-92, (2019) (PubMed).

Kaphalia, Srinivasan, Kakumanu, Kaphalia, Calhoun: "Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism." in: Alcoholism, clinical and experimental research, Vol. 43, Issue 8, pp. 1682-1694, (2019) (PubMed).

Gerbino, Bottillo, Milano, Lipari, Zio, Morlino, Mola, Procino, Re, Zachara, Grammatico, Svelto, Carmosino: "Functional Characterization of a Novel Truncating Mutation in Lamin A/C Gene in a Family with a Severe Cardiomyopathy with Conduction Defects." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 4, pp. 1559-1577, (2018) (PubMed).

Lu, Chen, Tang, Wang, Zhang: "GRP78 silencing enhances hyperoxia-induced alveolar epithelial cell apoptosis via CHOP pathway." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1493-1501, (2018) (PubMed).

Cai, Zheng, Gu, Wang, Wang, Yang, Zhang, Wang, Fu, Wang: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).

Liu, Shen, Wang, Liu, Zheng, Luo: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).

Yang, He, Li, Zhang, He, Duan, Huang, Xiang: "SWNHs (Single-Wall Carbon Nanohorns) Supervises Endoplasmic Reticulum (ER) Stress in Hepatocellular Carcinoma." in: Journal of nanoscience and nanotechnology, Vol. 18, Issue 10, pp. 6740-6745, (2018) (PubMed).

Dong, Liu, Meng, Liu, Bi, Wu, Jin, Yao, Tang, Wang, Li, Zhang, Yu, Zhan, Chen, Ge, Yang, Li: "Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination." in: Scientific reports, Vol. 6, pp. 32710, (2018) (PubMed).

Synonyme und alternative Namen zu PERK

eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3), eukaryotic translation initiation factor 2 alpha kinase 3 (Eif2ak3), AI427929, EIF2AK3, Pek, PEK, Perk, PERK, WRS

Bezeichner auf Proteinebene für PERK

  • eukaryotic translation initiation factor 2-alpha kinase 3
  • eukaryotic translation initiation factor 2-alpha kinase 3-like
  • PRKR-like endoplasmic reticulum kinase
  • pancreatic eIF2-alpha kinase
  • eukaryotic translation initiation factor 2 alpha kinase 3
  • hsPEK
  • pancreatic EIF2-alpha kinase
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