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Corticotropin Releasing Hormone (CRH) (C-Term) Peptid

CRH Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN2184150
  • Target Alle CRH Produkte
    CRH (Corticotropin Releasing Hormone (CRH))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 16
    Synthetic
    Applikation
    Western Blotting (WB), Blocking Peptide (BP)
    Sequenz
    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CRH (Corticotropin Releasing Hormone (CRH))
    Synonyme
    CRF Peptide, Gm1347 Peptide, crf Peptide, crh Peptide, zgc:101864 Peptide, CRH Peptide, corticoliberin Peptide, crhb Peptide, crh.1-a Peptide, crha Peptide, corticotropin releasing hormone Peptide, corticotropin releasing hormone b Peptide, corticotropin releasing hormone S homeolog Peptide, corticotropin releasing hormone L homeolog Peptide, Crh Peptide, CRH Peptide, crhb Peptide, crh Peptide, crh.S Peptide, crh.L Peptide
    Hintergrund
    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196
    Molekulargewicht
    21 kDa
    Gen-ID
    1392
    NCBI Accession
    NM_000756, NP_000747
    UniProt
    P06850
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