This is a synthetic peptide designed for use in combination with anti-Akirin2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Akirin2 forms a complex with YWHAB that acts to repress transcription of DUSP1. It is required for embryonic development and the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6.
Alias Symbols: 2700059D21Rik, AA114675, AA522011, AU019887, Akirin-2