F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptid
FBXW7
Reaktivität: Human
Wirt: Kaninchen
BP
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- Target Alle FBXW7 Produkte
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- Spezies
- Human
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Quelle
- Kaninchen
- Applikation
- Blocking Peptide (BP)
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- -80 °C
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- Target
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- Hintergrund
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
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