Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptid
CARD11
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CARD11 Produkte
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 Reaktivität: Human, Maus, Rind (Kuh), Hund Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Hintergrund
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 - Gen-ID
- 84433
- NCBI Accession
- NM_032415, NP_115791
- UniProt
- Q8TES3
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