Linker For Activation of T Cells (LAT) (Middle Region) Peptid
LAT
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle LAT Produkte
- LAT (Linker For Activation of T Cells (LAT))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- HTVAPWPPAY PPVTSYPPLS QPDLLPIPRS PQPLGGSHRT PSSRRDSDGA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-LAT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LAT (Linker For Activation of T Cells (LAT))
- Synonyme
- LAT Peptide, lat Peptide, LAT1 Peptide, pp36 Peptide, linker for activation of T-cells Peptide, linker for activation of T cells Peptide, LAT Peptide, lat Peptide, Lat Peptide
- Hintergrund
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The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: LAT1, pp36
Protein Size: 262 - Gen-ID
- 27040
- NCBI Accession
- NM_001014987, NP_001014987
- UniProt
- O43561
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