Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptid
MYD88
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle MYD88 Produkte
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- NVRTQVAADW TALAEEMDFE YLEIRQLETQ ADPTGRLLDA WQGRPGASVG
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MYD88 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Myeloid Differentiation Primary Response Gene (88) (MYD88) peptide
MYD88 Reaktivität: Human, Maus, Ratte, Hund Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Hintergrund
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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Alias Symbols: MYD88D
Protein Size: 296 - Gen-ID
- 4615
- NCBI Accession
- NM_001172566, NP_001166037
- UniProt
- Q99836
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