This is a synthetic peptide designed for use in combination with anti-MAP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
MAP4
(Microtubule-Associated Protein 4 (MAP4))
Synonyme
XMAP4 Peptide, mtap4 Peptide, AA407148 Peptide, MAP-4 Peptide, Mtap-4 Peptide, Mtap4 Peptide, microtubule associated protein 4 Peptide, microtubule associated protein 4 L homeolog Peptide, microtubule-associated protein 4 Peptide, MAP4 Peptide, map4.L Peptide, Map4 Peptide
Hintergrund
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.