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Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (N-Term) Peptid

MARCKS Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512417
  • Target Alle MARCKS Produkte
    MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GEAAVASSPS KANGQENGHV KVNGDASPAA AESGAKEELQ ANGSAPAADK
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- MARCKS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
    Hintergrund
    The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

    Alias Symbols: MACS, 80K-L, PKCSL, PRKCSL

    Protein Size: 332
    Gen-ID
    4082
    NCBI Accession
    NM_002356, NP_002347
    UniProt
    P29966
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