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Homeobox Protein Nkx-2.4 (LOC105228315) Peptid

LOC105228315 Reaktivität: Human Wirt: Synthetic WB
Produktnummer ABIN5671334
  • Target
    NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
    Spezies
    Human
    Quelle
    Synthetic
    Applikation
    Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-NKX21 antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
    Hintergrund
    This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

    Alias Symbols: NKX2A, TITF1, TTF1

    Protein Size: 371
    Molekulargewicht
    40 kDa
    Gen-ID
    7080
    NCBI Accession
    NP_003308
    UniProt
    P43699
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