This is a synthetic peptide designed for use in combination with anti- CLP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
CLP1
(Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
Synonyme
Heab Peptide, RGD1307679 Peptide, AI462438 Peptide, ACDP1 Peptide, CLP-1 Peptide, CGP-39 Peptide, GP-39 Peptide, SPC-40 Peptide, SPS-40 Peptide, YKL-40 Peptide, HEAB Peptide, hClp1 Peptide, fa28a12 Peptide, wu:fa28a12 Peptide, clp1 Peptide, cleavage and polyadenylation factor I subunit 1 Peptide, CLP1, cleavage and polyadenylation factor I subunit Peptide, cyclin and CBS domain divalent metal cation transport mediator 1 Peptide, chitinase 3-like 1 (cartilage glycoprotein-39) Peptide, cleavage and polyadenylation factor I subunit 1 L homeolog Peptide, Clp1 Peptide, CNNM1 Peptide, CHI3L1 Peptide, CLP1 Peptide, clp1 Peptide, clp1.L Peptide
Hintergrund
This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene.