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Catechol-O-Methyltransferase (COMT) (AA 51-271) Peptid
COMT
Reaktivität: Human
Wirt: Escherichia coli (E. coli)
SDS
Produktdetails
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Target
Alle COMT Produkte
COMT
(Catechol-O-Methyltransferase (COMT))
Protein-Typ
Recombinant
Protein Region
AA 51-271
Spezies
Human
Quelle
Alle Wirte für COMT Peptide
Escherichia coli (E. coli)
Applikation
SDS-PAGE (SDS)
Sequenz
MGDTKEQRIL NHVLQHAEPG NAQSVLEAID TYCEQKEWAM NVGDKKGKIV DAVIQEHQPS VLLELGAYCG YSAVRMARLL SPGARLITIE INPDCAAITQ RMVDFAGVKD KVTLVVGASQ DIIPQLKKKY DVDTLDMVFL DHWKDRYLPD TLLLEECGLL RKGTVLLADN VICPGAPDFL AHVRGSSCFE CTHYQSFLEY REVVDGLEKA IYKGPGSEAG P
Produktmerkmale
Purified recombinant Human COMT protein Expression System: E.coli Molecular weight on SDS-PAGE will appear higher.
Reinheit
> 95 % pure
Endotoxin-Niveau
< 1.0 EU per µg of protein (determined by LAL method)
Alternativen
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Anwendungsinformationen
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Applikationshinweise
COMT protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM MgCl2, and 10 % glycerol.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
RT/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
Antigendetails
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Target
COMT
(Catechol-O-Methyltransferase (COMT))
Synonyme
Comt1 Peptide, D16Wsu103e Peptide, D330014B15Rik Peptide, COMT Peptide, mb-comt Peptide, s-comt Peptide, comt Peptide, MGC154444 Peptide, zgc:114157 Peptide, si:dkey-13a21.15 Peptide, zK13A21.15 Peptide, zgc:162236 Peptide, catechol-O-methyltransferase Peptide, microRNA 4761 Peptide, catechol-O-methyltransferase S homeolog Peptide, methyltransferase Peptide, catechol-o-methyltransferase Peptide, catechol-O-methyltransferase a Peptide, catechol-O-methyltransferase b Peptide, catechol O-methyltransferase Peptide, COMT Peptide, Comt Peptide, MIR4761 Peptide, comt Peptide, comt.2 Peptide, comt.S Peptide, Rv1703c Peptide, Mb1729c Peptide, comta Peptide, comtb Peptide, LOC100354142 Peptide
Hintergrund
Catechol-O-methyltrasferase (COMT) is an enzyme that catalyses the transfer of the methyl group of S-adenosylmethionine (SAM) into catechol substrates such as levodopa, dopamine, epinephrine, and norepinephirine in the presence of Mg2+. COMT appears to be located in the postsynaptic neuron and plays roles in the metabolism of catechol estrogens and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT inhibitors prevent levodopa degradation, increase its availability and are used in the treatment of patients with Parkinson's disease. Recombinant human COMT protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Catechol-O-methyltransferase protein, COMT, Catechol-O-methyltransferase protein
Molekulargewicht
24.4 kDa (221 AA)
Zuletzt angesehen
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