A synthetic peptide for use as a blocking control in assays to test for specificity of C4 BPB antibody, Alternative Names: C4BPB control peptide, C4BPB antibody Blocking Peptide, Anti-C4BPB Blocking Peptide, Complement 4 Binding Protein Beta Blocking Peptide, C4BP, CBP-4, CBP 4, CBP-4 Blocking Peptide, CBP 4 Blocking Peptide
C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.