A synthetic peptide for use as a blocking control in assays to test for specificity of TRIM23 antibody, Alternative Names: TRIM23 control peptide, TRIM23 antibody Blocking Peptide, Anti-TRIM23 Blocking Peptide, tripartite motif-containing 23 Blocking Peptide, ARD1 Blocking Peptide, ARFD1 Blocking Peptide, RNF46 Blocking Peptide, TRIM23, TRIM-23, TRIM 23, TRIM-23 Blocking Peptide, TRIM 23 Blocking Peptide
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation.