A synthetic peptide for use as a blocking control in assays to test for specificity of TPM1 antibody, Alternative Names: Tropomyosin 1 control peptide, Tropomyosin 1 antibody Blocking Peptide, Anti-Tropomyosin 1 Blocking Peptide, TPM1 Blocking Peptide, CMH3 Blocking Peptide, TMSA Blocking Peptide, TPM1-alpha Blocking Peptide, Tropomyosin 1, Tropomyosin -1, Tropomyosin 1, Tropomyosin -1 Blocking Peptide, Tropomyosin 1 Blocking Peptide
TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.