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MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptid

MRE11A Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937579
  • Target Alle Mre11 (MRE11A) Produkte
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 8
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of MRE11 A antibody,
    Alternative Names: MRE11A control peptide, MRE11A antibody Blocking Peptide, Anti-MRE11A Blocking Peptide, MRE11 meiotic recombination 11 homolog A, S. cerevisiae Blocking Peptide, ATLD Blocking Peptide, HNGS1 Blocking Peptide, MRE11 Blocking Peptide, MRE11B Blocking Peptide, MRE11A, MREA-11, MREA 11, MREA-11 Blocking Peptide, MREA 11 Blocking Peptide
    Aufreinigung
    The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Hintergrund
    This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
    Molekulargewicht
    80 kDa
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