A synthetic peptide for use as a blocking control in assays to test for specificity of GPI antibody, Alternative Names: GPI control peptide, GPI antibody Blocking Peptide, Anti-GPI Blocking Peptide, glucose-6-phosphate isomerase Blocking Peptide, AMF Blocking Peptide, GNPI Blocking Peptide, NLK Blocking Peptide, PGI Blocking Peptide, PHI Blocking Peptide, SA36 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
GPI
(Glucose-6-Phosphate Isomerase (GPI))
Substanzklasse
Viral Protein
Hintergrund
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.