A synthetic peptide for use as a blocking control in assays to test for specificity of ALAD antibody, Alternative Names: ALAD control peptide, ALAD antibody Blocking Peptide, Anti-ALAD Blocking Peptide, Aminolevulinate Delta- Dehydratase Blocking Peptide, ALADH Blocking Peptide, MGC5057 Blocking Peptide
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.